Study of adsorption of the SARS-CoV-2 virus spike protein by vibrational spectroscopy using terahertz metamaterials

Adhesion of the spike protein of the SARS-CoV-2 virus is studied by vibrational spectroscopy using terahertz metamaterials. The features of metastructure absorption upon the deposition of histidine, albumin, and the receptor-binding domain of the spike protein films are investigated. An original tec...

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Bibliographic Details
Published in:Quantum electronics (Woodbury, N.Y.) N.Y.), 2022-01, Vol.52 (1), p.2-12
Main Authors: Konnikova, M.R., Cherkasova, O.P., Geints, T.A., Dizer, E.S., Man’kova, A.A., Vasilievskii, I.S., Butylin, A.A., Kistenev, Yu.V., Tuchin, V.V., Shkurinov, A.P.
Format: Article
Language:English
Subjects:
Adhesion
Albumins
Histidine
Metamaterials
Proteins
Severe acute respiratory syndrome coronavirus 2
Spectrum analysis
terahertz spectroscopy
Viruses
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Summary:Adhesion of the spike protein of the SARS-CoV-2 virus is studied by vibrational spectroscopy using terahertz metamaterials. The features of metastructure absorption upon the deposition of histidine, albumin, and the receptor-binding domain of the spike protein films are investigated. An original technique for quantitative assessment of the efficiency of virus adhesion on the metamaterial surfaces are proposed and experimentally tested.
ISSN:1063-7818
1468-4799
DOI:10.1070/QEL17960