Studying the Accumulation of Gadolinium in Human Brain Glioma for Gadolinium-Neutron Capture Therapy

The accumulation of gadolinium in human brain gliomas is estimated after a single intravenous administration of Magnevist. The study is conducted using samples excised during standard surgeries on human brain gliomas. Gadolinium is present in all five examined samples at concentrations of 0.0093 to...

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Bibliographic Details
Published in:Bulletin of the Russian Academy of Sciences. Physics 2021-12, Vol.85 (12), p.1445-1450
Main Authors: Kulabdullaev, G. A., Kim, A. A., Abdullaeva, G. A., Djuraeva, G. T., Sadikov, I. I., Yarmatov, B. Kh, Salimov, M. I., Kadirbekov, R. T., Kadirbekov, N. R., Mavlyanov, I. R.
Format: Article
Language:English
Subjects:
Accumulation
Brain
Gadolinium
Hadrons
Heavy Ions
Nuclear capture
Nuclear Physics
Physics
Physics and Astronomy
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Summary:The accumulation of gadolinium in human brain gliomas is estimated after a single intravenous administration of Magnevist. The study is conducted using samples excised during standard surgeries on human brain gliomas. Gadolinium is present in all five examined samples at concentrations of 0.0093 to 0.2384 ng mg –1 (ppm) of tumor tissue.
ISSN:1062-8738
1934-9432
DOI:10.3103/S1062873821120182