Degradation of Selected Antidepressants Sertraline and Citalopram in Ultrapure Water and Surface Water Using Gamma Radiation

Gamma radiation was applied to degradation selected antidepressants in ultrapure water and surface water. Additionally, the influence of typical radical scavengers like carbonate, nitrate and humic acid was determined. The cytotoxicity towards liver cells HepG2 and colon cells Caco2 were measured du...

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Bibliographic Details
Published in:Processes 2022-01, Vol.10 (1), p.63
Main Authors: Bojanowska-Czajka, Anna, Pyszynska, Marta, Majkowska-Pilip, Agnieszka, Wawrowicz, Kamil
Format: Article
Language:English
Subjects:
Antidepressants
Biodegradation
Citalopram
Colon
COVID-19
Cytotoxicity
Decomposition
Degradation
Drug dosages
Gamma rays
Hepatocytes
Humic acids
Hydroxyl radicals
Ionizing radiation
Pharmaceuticals
Plastic pollution
Pollutants
Radiation
Radiation measurement
Serotonin
Sertraline
Surface water
Toxicity
Water treatment
γ Radiation
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Summary:Gamma radiation was applied to degradation selected antidepressants in ultrapure water and surface water. Additionally, the influence of typical radical scavengers like carbonate, nitrate and humic acid was determined. The cytotoxicity towards liver cells HepG2 and colon cells Caco2 were measured during the radiation process. It was found that radiation technology, specifically ionizing radiation, can achieve satisfactory degradation efficiency with both SER and CIT. It was shown that the process of decomposition of the tested antidepressants with the highest efficiency occurs in the reaction with the hydroxyl radical.
ISSN:2227-9717
2227-9717
DOI:10.3390/pr10010063