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Triphala decorated multipotent green nanoparticles and its applications

[Display omitted] •Triphala nanoparticles (TNp) was formulated.•TNp possess potent antioxidant, antidiabetic and antibacterial activities.•TNp incorporated biomaterial controlled diabetic wound Causing E. coli. Diabetes Mellitus (DM) and its associated complications including neuropathy, retinopathy...

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Bibliographic Details
Published in:Materials letters 2022-02, Vol.308, p.131184, Article 131184
Main Authors: Ranjani, S., Hemalatha, S.
Format: Article
Language:English
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Summary:[Display omitted] •Triphala nanoparticles (TNp) was formulated.•TNp possess potent antioxidant, antidiabetic and antibacterial activities.•TNp incorporated biomaterial controlled diabetic wound Causing E. coli. Diabetes Mellitus (DM) and its associated complications including neuropathy, retinopathy, nephropathy, diabetic wound etc. are major problems all around the globe. Triphala, an ayurvedic formulation consists of fruit powders of Emblica officinalis, Terminalia belerica, and Terminalia chebula. The Triphala nanoparticles (TNp) was formulated, characterized and screened for its antioxidant, anti-diabetic, and antimicrobial potential. TNp was incorporated into medical fabrics and evaluated for its antibacterial potential against E. coli ATCC (25922) and multi drug resistant (MDR) E. coli isolated from diabetic wound. The results suggest that TNp possess antioxidant, antidiabetic and antibacterial activities. In future, TNp incorporated nano biomaterial might be an effective alternate to control diabetes related infection.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2021.131184