PeptCreatR: A Web App for Unique Peptides in Human

The concept of unique peptides implies that a peptide of a certain length can be assigned uniquely to certain protein of the whole proteome. It originated in the field of peptide identification using mass spectrometer. The creation of a database of unique peptides for an organism will be useful when...

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Bibliographic Details
Published in:International journal of peptide research and therapeutics 2022-03, Vol.28 (2), Article 64
Main Authors: Arumugaperumal, Arun, Velayudhan Krishna, Deepa, Alaguponniah, Sathyalakshmi, Nallaperumal, Krishnan, Sivasubramaniam, Sudhakar
Format: Article
Language:English
Subjects:
Animal Anatomy
Biochemistry
Biomedical and Life Sciences
Histology
Life Sciences
Molecular Medicine
Morphology
Peptides
Pharmaceutical Sciences/Technology
Pharmacology/Toxicology
Polymer Sciences
Proteins
Proteomes
Proteomics
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Summary:The concept of unique peptides implies that a peptide of a certain length can be assigned uniquely to certain protein of the whole proteome. It originated in the field of peptide identification using mass spectrometer. The creation of a database of unique peptides for an organism will be useful when techniques develop to instantaneously identify a protein’s identity based on its unique sequence. The unique proteome of human was downloaded from UniProt database. The unique peptides for the protein sequences were found out by a custom made script in R programming. The identified unique peptides were incorporated in an R shiny web application and is hosted at https://arun-biotechnologist.shinyapps.io/createpept/ . This will serve as a useful reference for researchers in the field of proteomics. Graphical abstract
ISSN:1573-3149
1573-3904
DOI:10.1007/s10989-022-10375-4