Biosurfactant electrospun nanofibers exhibit minimal side effects on the structure and function of the liver tissue in male rat model

Oil spills can result in significant damage to marine estuaries, rivers, lakes, wetlands, and shorelines. Electrospun nanofibers containing biosurfactant (ENFs) can be used to clean oil spills up and protect the environmental biology. Present work aimed to study the side-effects of prepared nanofibe...

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Bibliographic Details
Published in:Environmental science and pollution research international 2020-11, Vol.27 (32), p.40009-40019
Main Authors: Ebaid, Hossam Abd Rabou, Abdel-Mageed, Ahmed, Al-Tamimi, Jameel Homoud, Hassan, Iftekhar, Rady, Ahmed Mostafa, El-Newehy, Mohamed Hassan, Mashaly, Ashraf Mohamed, Abdel-Megeed, Ahmed AbdelFattah Mahmoud, Alhazza, Ibrahim, Abdel-Halim, Essam Sayed, Salem, Abdelfattah Zeidan Mohamed
Format: Article
Language:English
Subjects:
Animal models
Aquatic Pollution
Atmospheric Protection/Air Quality Control/Air Pollution
Earth and Environmental Science
Ecotoxicology
Electrospinning
Environment
Environmental Chemistry
Environmental Health
Environmental science
Estuaries
Lakes
Leukocytes (neutrophilic)
Liver
Nanofibers
Oil spills
Oxidative stress
Research Article
Shorelines
Side effects
Structure-function relationships
Surfactants
Waste Water Technology
Water Management
Water Pollution Control
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Summary:Oil spills can result in significant damage to marine estuaries, rivers, lakes, wetlands, and shorelines. Electrospun nanofibers containing biosurfactant (ENFs) can be used to clean oil spills up and protect the environmental biology. Present work aimed to study the side-effects of prepared nanofibers on animal models. Screening of the prepared ECNFs on animals showed that three of them (PVA-5, PEO-1, and PEO-5) are safe to hepatic tissues and liver functions. Furthermore, oxidative stress did not change after using these nanofibers. The PVA-1 nanofibers, however, were found to cause major pathological changes in the liver tissue. In addition, PVA-1 nanofibers were proved to alter the total white blood count and the neutrophil percentages significantly in comparison to the control. In conclusion, PVA-5, PEO-1, and PEO-5 are safe to hepatic tissues and liver functions.
ISSN:0944-1344
1614-7499
DOI:10.1007/s11356-020-10077-8