Sesquiterpenoids from the Edible Mushroom Pleurotus nebrodensis

Pleunebron A ( 1 ), a new cadinane sesquiterpenoid, together with three known drimane sesquiterpenoids ( 2–4 ), was isolated from cultures of the edible mushroom Pleurotus nebrodensis . Their structures were elucidated on the basis of extensive spectroscopic methods. Compounds 1 and 2 were tested fo...

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Bibliographic Details
Published in:Chemistry of natural compounds 2022, Vol.58 (1), p.37-39
Main Authors: Ding, Jian-Hai, Han, Xin-Ning, Liu, Shi-Wei, Li, Zheng-Hui, Feng, Tao, Liu, Ji-Kai
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Hydroxysteroids
Mushrooms
Organic Chemistry
Plant Sciences
Sesquiterpenes
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Summary:Pleunebron A ( 1 ), a new cadinane sesquiterpenoid, together with three known drimane sesquiterpenoids ( 2–4 ), was isolated from cultures of the edible mushroom Pleurotus nebrodensis . Their structures were elucidated on the basis of extensive spectroscopic methods. Compounds 1 and 2 were tested for their cytotoxicities against five human cancer cell lines and for their inhibitory activity against isozymes of 11 β -hydroxysteroid dehydrogenases (11 β -HSD).
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03592-2