Understanding Nanomaterial–Liver Interactions to Facilitate the Development of Safer Nanoapplications (Adv. Mater. 11/2022)

Nanomedicine The liver is the primary accumulation site for intravenously administered nanocarriers or incidental nanoparticles that gain access to the systemic circulation. Liver distribution and cellular uptake of nanoparticles by various liver cells could influence the therapeutic efficacy. Under...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2022-03, Vol.34 (11), p.n/a
Main Authors: Li, Jiulong, Chen, Chunying, Xia, Tian
Format: Article
Language:English
Subjects:
cell‐type‐specific uptake
Liver
mode of action
Nanomaterials
nanomedicine
Nanoparticles
nanosafety
nano–liver interaction
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Summary:Nanomedicine The liver is the primary accumulation site for intravenously administered nanocarriers or incidental nanoparticles that gain access to the systemic circulation. Liver distribution and cellular uptake of nanoparticles by various liver cells could influence the therapeutic efficacy. Understanding nano–liver interactions is critical for the design of much safer and more effective nano‐theranostics to treat diverse diseases, as discussed by Chunying Chen, Tian Xia, and Jiulong Li in article number 2106456.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202270086