Hyperbaric reactions in organic synthesis. Progress from 2006 to 2021

This comprehensive review summarizes the published literature data concerning above 1 kbar reactions for the purposes of preparative organic synthesis (more than 50 mg of the initial substance) from 2006 to the beginning of 2021 and highlights the obstacles, which were overcome by the use of a high-...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2022-03, Vol.2 (12), p.232-2355
Main Authors: Rulev, Alexander Yu, Zubkov, Fedor I
Format: Article
Language:English
Subjects:
Chemical bonds
Chemical synthesis
Chemistry Techniques, Synthetic
Literature reviews
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Summary:This comprehensive review summarizes the published literature data concerning above 1 kbar reactions for the purposes of preparative organic synthesis (more than 50 mg of the initial substance) from 2006 to the beginning of 2021 and highlights the obstacles, which were overcome by the use of a high-pressure technique. The review covers around 100 references. This account systematizes a hundred papers (2006-2021 yy) in order to highlight the advantages of hyperbaric conditions (1-20 kbar) in preparative organic synthesis.
ISSN:1477-0520
1477-0539
DOI:10.1039/d1ob01423d