Effect of Adding a 2-Month Consequent Continuous and Interval Elliptical Aerobic Training to Once-Daily 5-mg Tadalafil Administration on Erectile Dysfunction in Obese Men

Exercise (Ex) shares the first-line approach with pharmacological inhibitors of phosphodiesterase type 5 (PDE5-Is), including tadalafil, in the treatment of erectile dysfunction (ED) in obese men. The effect of elliptical training (ET) on ED was not questioned in the literature. This study aimed to...

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Bibliographic Details
Published in:Sexuality and disability 2022-03, Vol.40 (1), p.129-139
Main Authors: Ismail, Ali Mohamed Ali, Abdelghany, Abdelrhman Ismail
Format: Article
Language:English
Subjects:
Aerobic exercise
Aging
Behavioral Science and Psychology
Blood pressure
Body Composition
Body mass index
Community and Environmental Psychology
Density
Erectile dysfunction
Fasting
Glucose
Homeostasis
Insulin
Males
Management
Men
Obesity
Original Paper
Psychology
Rehabilitation Medicine
Scientific Concepts
Sexual Behavior
Triglycerides
Urology
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Summary:Exercise (Ex) shares the first-line approach with pharmacological inhibitors of phosphodiesterase type 5 (PDE5-Is), including tadalafil, in the treatment of erectile dysfunction (ED) in obese men. The effect of elliptical training (ET) on ED was not questioned in the literature. This study aimed to clarify the effect of adding a 2-month consequent continuous and interval ET to once-daily 5-mg tadalafil administration on ED in obese men. Sixty obese men aged 34–56 years with ED were randomly assigned to the Ex group (n = 30) and the non-Ex group (n = 30). Both groups received 8-week oral tadalafil administration (five-milligram tablet, one time/day). Ex group only received a 1-h concurrent interval and continuous ET (three times/week for 2 months). Homeostasis model assessment of insulin resistance (HOMA-IR), insulin, body mass index (BMI), the circumference of the waist (WC), systolic blood pressure (SBP), high-density lipoprotein (HDL), diastolic blood pressure (DBP), triglycerides (TG), Five-Item Version of International Index of Erectile Dysfunction (IIEF-5), and fasting blood glucose (FBG) were screened before and after the trial. A significant statistical difference of all measures was ascertained from the within-Ex-group comparison (P 
ISSN:0146-1044
1573-6717
DOI:10.1007/s11195-021-09720-0