A stochastic inspection about genetic variants of Covid-19 circulating in Brazil during 2020

In this article, we investigate the existence of genetic variants of Covid-19 circulating in Brazil in the 2020 outbreak. We apply the findings of [1] about the Partition Markov Model (PMM) with gap in genetic sequences of Covid-19, see also [2]. Using a metric on those models, we define the proximi...

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Bibliographic Details
Main Authors: García, Jesús E., González-López, V. A., Tasca, G. H.
Format: Conference Proceeding
Language:English
Subjects:
Coronaviruses
COVID-19
Gene sequencing
Inspection
Markov chains
Outbreaks
Online Access:Get full text
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Summary:In this article, we investigate the existence of genetic variants of Covid-19 circulating in Brazil in the 2020 outbreak. We apply the findings of [1] about the Partition Markov Model (PMM) with gap in genetic sequences of Covid-19, see also [2]. Using a metric on those models, we define the proximity between complete genomic sequences of the NCBI base. We see that two groups can be identified among the five available sequences that come from Brazil. To verify our claims, we implement a more complete comparison consisting of fourteen sequences, including sequences from Spain and Italy. Such comparison indicates the existence of two groups, where each group includes one from the previously identified Brazilian groups. Then, we found at least two variants of Covid-19 circulating in Brazil during the 2020 outbreak.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0081337