Changed pattern of SERS hotspots by Ag nanoparticle growth under magnetic field for biomarker detection

As an important marker of Hepatocellular carcinoma (HCC), AFP-L3 has attracted attention. In this study, the surface-plasmon-assisted Ag nanoparticles symmetrical growth technology under magnetic field is used to fabricate the six-nanohole nanojar array containing Ag nanoparticles as the sensing sub...

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Bibliographic Details
Published in:Journal of materials science 2022-04, Vol.57 (13), p.6943-6952
Main Authors: Zhang, Yongjun, Zhao, Xiaoyu, Zhu, Qi, Cheng, Mingyu, Xu, Wei, Wang, Yaxin, Zhu, Aonan, Gao, Renxian, Zhang, Jian, Zhang, Xiaolong
Format: Article
Language:English
Subjects:
Alpha fetoproteins
Biomarkers
Characterization and Evaluation of Materials
Chemistry and Materials Science
Classical Mechanics
Composites & Nanocomposites
Crystallography and Scattering Methods
Magnetic fields
Materials Science
Nanoparticles
Polymer Sciences
Silver
Solid Mechanics
Substrates
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Summary:As an important marker of Hepatocellular carcinoma (HCC), AFP-L3 has attracted attention. In this study, the surface-plasmon-assisted Ag nanoparticles symmetrical growth technology under magnetic field is used to fabricate the six-nanohole nanojar array containing Ag nanoparticles as the sensing substrate. The displacement of SERS signal of the optimized structure is used to detect HCC marker AFP-L3. This method has good stability, high accuracy and has great potential in the early diagnosis of HCC.
ISSN:0022-2461
1573-4803
DOI:10.1007/s10853-022-07026-w