Ionic liquid‐assisted synthesis of 2‐amino‐3‐cyano‐4H‐chromenes: A sustainable overview

In advanced research, the role of ionic liquid is gradually enhanced as an alternative finding. For a long time, many strategies have been developed based on the ionic liquid conveying the role of greener solvents or catalysts. In the case of multi‐component synthesis, ionic liquids have a wide rang...

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Bibliographic Details
Published in:Journal of heterocyclic chemistry 2022-04, Vol.59 (4), p.633-654
Main Authors: Chatterjee, Rana, Bhukta, Swadhapriya, Dandela, Rambabu
Format: Article
Language:English
Subjects:
Biological activity
Chemical bonds
Ionic liquids
Ions
Online Access:Get full text
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Summary:In advanced research, the role of ionic liquid is gradually enhanced as an alternative finding. For a long time, many strategies have been developed based on the ionic liquid conveying the role of greener solvents or catalysts. In the case of multi‐component synthesis, ionic liquids have a wide range of applications to revise a method in a sustainable and greener approach. The last two decades have given a number of methods to achieve the 4H‐chromene derivatives by applying different types of ionic liquids. Especially, 2‐amino‐3‐cyano‐4H‐chromene moiety that exhibits pharmacological and biological activity, have been synthesized using simple or functionalized ionic liquids such as basic, acidic, neural, metal‐tagged, or carbon‐oriented ionic liquid. In this review, we have concised the multicomponent reactions that have been reported to synthesize the 4H‐chromene derivatives following the versatility of ionic liquids.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.4417