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Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section
A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was...
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Published in: | Journal of medical primatology 2022-06, Vol.51 (3), p.195-198 |
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creator | Kim, Jong‐Min Kwak, Jina Kim, Joo‐Il Kim, Donghun Kang, Byeong‐Cheol |
description | A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. To the best of our knowledge, this is the first case report of thrombotic microangiopathy in a marmoset with preeclampsia. |
doi_str_mv | 10.1111/jmp.12576 |
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Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. To the best of our knowledge, this is the first case report of thrombotic microangiopathy in a marmoset with preeclampsia.</description><identifier>ISSN: 0047-2565</identifier><identifier>EISSN: 1600-0684</identifier><identifier>DOI: 10.1111/jmp.12576</identifier><identifier>PMID: 35266161</identifier><language>eng</language><publisher>Denmark: Wiley Subscription Services, Inc</publisher><subject>Animals ; Anorexia ; Callithrix ; Callithrix jacchus ; Callitrichinae ; Cesarean section ; Cesarean Section - adverse effects ; Cesarean Section - veterinary ; common marmoset ; Diagnosis ; Female ; Hypothermia ; Pre-eclampsia ; Pre-Eclampsia - diagnosis ; Preeclampsia ; Pregnancy ; Surgery ; Thrombocytopenia ; Thrombotic Microangiopathies - diagnosis ; Thrombotic Microangiopathies - etiology ; Thrombotic Microangiopathies - therapy ; Thrombotic microangiopathy</subject><ispartof>Journal of medical primatology, 2022-06, Vol.51 (3), p.195-198</ispartof><rights>2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2022 John Wiley & Sons A/S</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c2806-f8b345a33f6971e3313dba398b1f3b4b6214162e84ac85803e031aa6b692d5a83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35266161$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Jong‐Min</creatorcontrib><creatorcontrib>Kwak, Jina</creatorcontrib><creatorcontrib>Kim, Joo‐Il</creatorcontrib><creatorcontrib>Kim, Donghun</creatorcontrib><creatorcontrib>Kang, Byeong‐Cheol</creatorcontrib><title>Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section</title><title>Journal of medical primatology</title><addtitle>J Med Primatol</addtitle><description>A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. To the best of our knowledge, this is the first case report of thrombotic microangiopathy in a marmoset with preeclampsia.</description><subject>Animals</subject><subject>Anorexia</subject><subject>Callithrix</subject><subject>Callithrix jacchus</subject><subject>Callitrichinae</subject><subject>Cesarean section</subject><subject>Cesarean Section - adverse effects</subject><subject>Cesarean Section - veterinary</subject><subject>common marmoset</subject><subject>Diagnosis</subject><subject>Female</subject><subject>Hypothermia</subject><subject>Pre-eclampsia</subject><subject>Pre-Eclampsia - diagnosis</subject><subject>Preeclampsia</subject><subject>Pregnancy</subject><subject>Surgery</subject><subject>Thrombocytopenia</subject><subject>Thrombotic Microangiopathies - diagnosis</subject><subject>Thrombotic Microangiopathies - etiology</subject><subject>Thrombotic Microangiopathies - therapy</subject><subject>Thrombotic microangiopathy</subject><issn>0047-2565</issn><issn>1600-0684</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp1kMtOGzEUQK2qqKS0i_5AZakbWAzY40c8yypAAYHoAtaja8dDHI3tqe2o5AP4b0xD2XE31pWOjnUPQt8oOaZ1TtZ-OqatmMsPaEYlIQ2Rin9EM0L4vGmFFPvoc85rQgjjHf-E9plopaSSztDTqYOHELPLOA64rFL0OhZnsHcmRQgPLk5QVlvsAp6StWYEP2UHL3tZWWyi9zFgD8nHbAs-XMA4uupxj3gNxqw2-QhDWOKSLBRvQ8F6i43NUPeAszXFxfAF7Q0wZvv19T1A9-dnd4uL5vr21-Xi53VjWkVkMyjNuADGBtnNqWWMsqUG1ilNB6a5li3lVLZWcTBKKMIsYRRAatm1SwGKHaAfO--U4p-NzaVfx00K9cu-lYKrjiguKnW0o2qBnJMd-im5euG2p6R_Cd7X4P2_4JX9_mrcaG-Xb-T_whU42QF_3Wi375v6q5vfO-Uz4imLxQ</recordid><startdate>202206</startdate><enddate>202206</enddate><creator>Kim, Jong‐Min</creator><creator>Kwak, Jina</creator><creator>Kim, Joo‐Il</creator><creator>Kim, Donghun</creator><creator>Kang, Byeong‐Cheol</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope></search><sort><creationdate>202206</creationdate><title>Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section</title><author>Kim, Jong‐Min ; Kwak, Jina ; Kim, Joo‐Il ; Kim, Donghun ; Kang, Byeong‐Cheol</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2806-f8b345a33f6971e3313dba398b1f3b4b6214162e84ac85803e031aa6b692d5a83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>Anorexia</topic><topic>Callithrix</topic><topic>Callithrix jacchus</topic><topic>Callitrichinae</topic><topic>Cesarean section</topic><topic>Cesarean Section - adverse effects</topic><topic>Cesarean Section - veterinary</topic><topic>common marmoset</topic><topic>Diagnosis</topic><topic>Female</topic><topic>Hypothermia</topic><topic>Pre-eclampsia</topic><topic>Pre-Eclampsia - diagnosis</topic><topic>Preeclampsia</topic><topic>Pregnancy</topic><topic>Surgery</topic><topic>Thrombocytopenia</topic><topic>Thrombotic Microangiopathies - diagnosis</topic><topic>Thrombotic Microangiopathies - etiology</topic><topic>Thrombotic Microangiopathies - therapy</topic><topic>Thrombotic microangiopathy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Jong‐Min</creatorcontrib><creatorcontrib>Kwak, Jina</creatorcontrib><creatorcontrib>Kim, Joo‐Il</creatorcontrib><creatorcontrib>Kim, Donghun</creatorcontrib><creatorcontrib>Kang, Byeong‐Cheol</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of medical primatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Jong‐Min</au><au>Kwak, Jina</au><au>Kim, Joo‐Il</au><au>Kim, Donghun</au><au>Kang, Byeong‐Cheol</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section</atitle><jtitle>Journal of medical primatology</jtitle><addtitle>J Med Primatol</addtitle><date>2022-06</date><risdate>2022</risdate><volume>51</volume><issue>3</issue><spage>195</spage><epage>198</epage><pages>195-198</pages><issn>0047-2565</issn><eissn>1600-0684</eissn><abstract>A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. To the best of our knowledge, this is the first case report of thrombotic microangiopathy in a marmoset with preeclampsia.</abstract><cop>Denmark</cop><pub>Wiley Subscription Services, Inc</pub><pmid>35266161</pmid><doi>10.1111/jmp.12576</doi><tpages>4</tpages></addata></record> |
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subjects | Animals Anorexia Callithrix Callithrix jacchus Callitrichinae Cesarean section Cesarean Section - adverse effects Cesarean Section - veterinary common marmoset Diagnosis Female Hypothermia Pre-eclampsia Pre-Eclampsia - diagnosis Preeclampsia Pregnancy Surgery Thrombocytopenia Thrombotic Microangiopathies - diagnosis Thrombotic Microangiopathies - etiology Thrombotic Microangiopathies - therapy Thrombotic microangiopathy |
title | Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section |
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