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Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section

A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was...

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Published in:Journal of medical primatology 2022-06, Vol.51 (3), p.195-198
Main Authors: Kim, Jong‐Min, Kwak, Jina, Kim, Joo‐Il, Kim, Donghun, Kang, Byeong‐Cheol
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creator Kim, Jong‐Min
Kwak, Jina
Kim, Joo‐Il
Kim, Donghun
Kang, Byeong‐Cheol
description A pregnant common marmoset (Callithrix jacchus) showed tachypnea, hypothermia, and anorexia at close to the expected delivery date. Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. To the best of our knowledge, this is the first case report of thrombotic microangiopathy in a marmoset with preeclampsia.
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Severe anemia and thrombocytopenia, schistocytes, and high levels of LDH and D‐dimer were observed. Three days after the onset of clinical signs, a cesarean section was conducted due to stillbirth. Marmoset immediately recovered after surgery, and the abnormal CBC and blood chemistry parameters before surgery returned to the normal ranges. Diagnosis of pregnancy‐associated thrombotic microangiopathy was made because removal of infant and placenta is curative. 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subjects Animals
Anorexia
Callithrix
Callithrix jacchus
Callitrichinae
Cesarean section
Cesarean Section - adverse effects
Cesarean Section - veterinary
common marmoset
Diagnosis
Female
Hypothermia
Pre-eclampsia
Pre-Eclampsia - diagnosis
Preeclampsia
Pregnancy
Surgery
Thrombocytopenia
Thrombotic Microangiopathies - diagnosis
Thrombotic Microangiopathies - etiology
Thrombotic Microangiopathies - therapy
Thrombotic microangiopathy
title Diagnosis of thrombotic microangiopathy in preeclampsia in the common marmoset (Callithrix jacchus) and treatment by cesarean section
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