Doing the Molecular Splits: Hands-On Demonstration Tips to Promote Student Engagement Using Split Inteins in Molecular Biology

Engaging undergraduates in the mechanisms of post-translational modifications lies at the heart of molecular and cell biology education. An important challenge for science educators is developing inclusive and equitable approaches and hands-on demonstrations to clarify post-translational modificatio...

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Bibliographic Details
Published in:The American biology teacher 2020-09, Vol.82 (7), p.499-502
Main Authors: Kao, Robert M., Liu, Yan, Bai, Jihong
Format: Article
Language:English
Subjects:
Biology
Caenorhabditis elegans
College students
equity
hands-on demonstration
inclusion
Inteins
Molecular biology
Pedagogy
Post-translation
Recycled materials
Science education
Splicing
split intein
Student participation
synaptojanin
three-dimensional learning framework
TIPS, TRICKS & TECHNIQUES
Translation
Citations: Items that this one cites
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Summary:Engaging undergraduates in the mechanisms of post-translational modifications lies at the heart of molecular and cell biology education. An important challenge for science educators is developing inclusive and equitable approaches and hands-on demonstrations to clarify post-translational modification mechanisms, such as the protein-splicing mechanism called split inteins. Here, we describe step-by-step assembly of recycled materials to help clarify the molecular action of split inteins in inclusive classroom teaching settings.
ISSN:0002-7685
1938-4211
DOI:10.1525/abt.2020.82.7.499