Disease-specific quality of life in patients with diabetic neuropathy

Objectives: To compare health-related quality of life (HRQoL) among patients with diabetes mellitus (DM) and diabetic neuropathy (DN) (D+N) with patients with DM without DN (D-DN) and healthy participants. To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study includ...

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Published in:Saudi medical journal 2022-04, Vol.43 (4), p.408-417
Main Authors: Alghamdi, Mushabab, Owolabi, Lukman F, Adamu, Bappa, Taura, Magaji G, Jibo, Abubakar, Almansour, Mohammed, Alaklabi, Saeed N, Alghamdi, Mohammed A, Imam, Isa A, Abdelrazak, Reda, Rafaat, Ahmad, Aliyu, Muktar H
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Language:English
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Complications and side effects
Diabetes
Diabetic neuropathies
Diabetic neuropathy
Disability
Health aspects
Quality of life
Surveys
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container_issue 4
container_start_page 408
container_title Saudi medical journal
container_volume 43
creator Alghamdi, Mushabab
Owolabi, Lukman F
Adamu, Bappa
Taura, Magaji G
Jibo, Abubakar
Almansour, Mohammed
Alaklabi, Saeed N
Alghamdi, Mohammed A
Imam, Isa A
Abdelrazak, Reda
Rafaat, Ahmad
Aliyu, Muktar H
description Objectives: To compare health-related quality of life (HRQoL) among patients with diabetes mellitus (DM) and diabetic neuropathy (DN) (D+N) with patients with DM without DN (D-DN) and healthy participants. To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study included 306 participants residing in Bisha, Saudi Arabia. Patients with DM were screened for DN using the Michigan Neuropathy Screening Instrument. Neuropathy severity, disability and HRQoL were determined using the Neuropathy Severity Scale (NSS), the Neuropathy Disability Score (NDS), and the Norfolk Quality of Life-Diabetic Neuropathy (QOLDN) tool, respectively. Nerve conduction studies (NCSs) were also performed. Results: The D+DN group had poorer overall and domain HRQoL scores compared to the D-DN group (p
doi_str_mv 10.15537/smj.2022.43.4.20210861
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To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study included 306 participants residing in Bisha, Saudi Arabia. Patients with DM were screened for DN using the Michigan Neuropathy Screening Instrument. Neuropathy severity, disability and HRQoL were determined using the Neuropathy Severity Scale (NSS), the Neuropathy Disability Score (NDS), and the Norfolk Quality of Life-Diabetic Neuropathy (QOLDN) tool, respectively. Nerve conduction studies (NCSs) were also performed. Results: The D+DN group had poorer overall and domain HRQoL scores compared to the D-DN group (p<0.001). There was a strong correlation between overall HRQoL score and both NDS and NSS scores in the D+DN group (p= -0.71 and p<0.0001; p= -0.81 and p<0.0001, respectively). There was also a significant difference in all mean HRQoL domain scores between D+DN participants with normal and abnormal NCS. Physical inactivity (p=0.043), duration of DM (p<0.0001), abnormal NCS, NSS (p<0.0001), and NDS (p<0.0001) predicted HRQoL in the D+DN group. Conclusion: D+DN participants had a worse HRQoL compared with D-DN and healthy counterparts. NDS, NNS, physical inactivity, abnormal NCS, and duration of DM independently predicted poor HRQoL in D+DN participants. Keywords: quality of life, diabetes melitus, disease-specific [phrase omitted]]]></description><identifier>ISSN: 0379-5284</identifier><identifier>EISSN: 1658-3175</identifier><identifier>DOI: 10.15537/smj.2022.43.4.20210861</identifier><language>eng</language><publisher>Riyadh: Saudi Medical Journal</publisher><subject>Complications and side effects ; Diabetes ; Diabetic neuropathies ; Diabetic neuropathy ; Disability ; Health aspects ; Quality of life ; Surveys</subject><ispartof>Saudi medical journal, 2022-04, Vol.43 (4), p.408-417</ispartof><rights>COPYRIGHT 2022 Saudi Medical Journal</rights><rights>Saudi Medical Journal 2022. This work is licensed under the Creative Commons Attribution – Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0 (the “License”). 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To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study included 306 participants residing in Bisha, Saudi Arabia. Patients with DM were screened for DN using the Michigan Neuropathy Screening Instrument. Neuropathy severity, disability and HRQoL were determined using the Neuropathy Severity Scale (NSS), the Neuropathy Disability Score (NDS), and the Norfolk Quality of Life-Diabetic Neuropathy (QOLDN) tool, respectively. Nerve conduction studies (NCSs) were also performed. Results: The D+DN group had poorer overall and domain HRQoL scores compared to the D-DN group (p<0.001). There was a strong correlation between overall HRQoL score and both NDS and NSS scores in the D+DN group (p= -0.71 and p<0.0001; p= -0.81 and p<0.0001, respectively). There was also a significant difference in all mean HRQoL domain scores between D+DN participants with normal and abnormal NCS. Physical inactivity (p=0.043), duration of DM (p<0.0001), abnormal NCS, NSS (p<0.0001), and NDS (p<0.0001) predicted HRQoL in the D+DN group. Conclusion: D+DN participants had a worse HRQoL compared with D-DN and healthy counterparts. NDS, NNS, physical inactivity, abnormal NCS, and duration of DM independently predicted poor HRQoL in D+DN participants. Keywords: quality of life, diabetes melitus, disease-specific [phrase omitted]]]></description><subject>Complications and side effects</subject><subject>Diabetes</subject><subject>Diabetic neuropathies</subject><subject>Diabetic neuropathy</subject><subject>Disability</subject><subject>Health aspects</subject><subject>Quality of life</subject><subject>Surveys</subject><issn>0379-5284</issn><issn>1658-3175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNptkUtLA0EMgAdRsFZ_gwued828d4-l1gcUvPQ-TKcZO2Vfndki_feuVhFBckhIviSHj5BbCgWVkuv71OwKBowVghfis6JQKnpGJlTJMudUy3MyAa6rXLJSXJKrlHYAXClQE7J4CAltwjz16IIPLtsfbB2GY9b5rA4es9BmvR0CtkPK3sOwzTbBrnEYyRYPsRtn2-M1ufC2Tnjznadk9bhYzZ_z5evTy3y2zJ2QesgFo4yj9wIVam-VsBsEC4JpQOsl0DV3Suk1rZz1nnFXAjrJS1VRpUrJp-TudLaP3f6AaTC77hDb8aNhSlEKoqzgl3qzNZrQ-m6I1jUhOTPTwCnnWlUjVfxDjbHBJriuRR_G_p8FfVpwsUspojd9DI2NR0PBfJkwownzacIIboT5McE_AFAbe0w</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Alghamdi, Mushabab</creator><creator>Owolabi, Lukman F</creator><creator>Adamu, Bappa</creator><creator>Taura, Magaji G</creator><creator>Jibo, Abubakar</creator><creator>Almansour, Mohammed</creator><creator>Alaklabi, Saeed N</creator><creator>Alghamdi, Mohammed A</creator><creator>Imam, Isa A</creator><creator>Abdelrazak, Reda</creator><creator>Rafaat, Ahmad</creator><creator>Aliyu, Muktar H</creator><general>Saudi Medical Journal</general><general>Prince Sultan Military Medical City (PSMMC)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20220401</creationdate><title>Disease-specific quality of life in patients with diabetic neuropathy</title><author>Alghamdi, Mushabab ; Owolabi, Lukman F ; Adamu, Bappa ; Taura, Magaji G ; Jibo, Abubakar ; Almansour, Mohammed ; Alaklabi, Saeed N ; Alghamdi, Mohammed A ; Imam, Isa A ; Abdelrazak, Reda ; Rafaat, Ahmad ; Aliyu, Muktar H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-42123eff4e6e7fa64ade0a04270eaf501b3c667b19caff23c80ec53869166853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Complications and side effects</topic><topic>Diabetes</topic><topic>Diabetic neuropathies</topic><topic>Diabetic neuropathy</topic><topic>Disability</topic><topic>Health aspects</topic><topic>Quality of life</topic><topic>Surveys</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Alghamdi, Mushabab</creatorcontrib><creatorcontrib>Owolabi, Lukman F</creatorcontrib><creatorcontrib>Adamu, Bappa</creatorcontrib><creatorcontrib>Taura, Magaji G</creatorcontrib><creatorcontrib>Jibo, Abubakar</creatorcontrib><creatorcontrib>Almansour, Mohammed</creatorcontrib><creatorcontrib>Alaklabi, Saeed N</creatorcontrib><creatorcontrib>Alghamdi, Mohammed A</creatorcontrib><creatorcontrib>Imam, Isa A</creatorcontrib><creatorcontrib>Abdelrazak, Reda</creatorcontrib><creatorcontrib>Rafaat, Ahmad</creatorcontrib><creatorcontrib>Aliyu, Muktar H</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health &amp; 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To evaluate factors associated with poor HRQoL in patients with DN. Methods: This study included 306 participants residing in Bisha, Saudi Arabia. Patients with DM were screened for DN using the Michigan Neuropathy Screening Instrument. Neuropathy severity, disability and HRQoL were determined using the Neuropathy Severity Scale (NSS), the Neuropathy Disability Score (NDS), and the Norfolk Quality of Life-Diabetic Neuropathy (QOLDN) tool, respectively. Nerve conduction studies (NCSs) were also performed. Results: The D+DN group had poorer overall and domain HRQoL scores compared to the D-DN group (p<0.001). There was a strong correlation between overall HRQoL score and both NDS and NSS scores in the D+DN group (p= -0.71 and p<0.0001; p= -0.81 and p<0.0001, respectively). There was also a significant difference in all mean HRQoL domain scores between D+DN participants with normal and abnormal NCS. Physical inactivity (p=0.043), duration of DM (p<0.0001), abnormal NCS, NSS (p<0.0001), and NDS (p<0.0001) predicted HRQoL in the D+DN group. Conclusion: D+DN participants had a worse HRQoL compared with D-DN and healthy counterparts. NDS, NNS, physical inactivity, abnormal NCS, and duration of DM independently predicted poor HRQoL in D+DN participants. Keywords: quality of life, diabetes melitus, disease-specific [phrase omitted]]]></abstract><cop>Riyadh</cop><pub>Saudi Medical Journal</pub><doi>10.15537/smj.2022.43.4.20210861</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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subjects Complications and side effects
Diabetes
Diabetic neuropathies
Diabetic neuropathy
Disability
Health aspects
Quality of life
Surveys
title Disease-specific quality of life in patients with diabetic neuropathy
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