Cigarette smoking and risk of cerebral sinus thrombosis in oral contraceptive users: a case-control study

Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospital-based, multicentric, case-co...

Full description

Saved in:
Bibliographic Details
Published in:Neurological sciences 2005-12, Vol.26 (5), p.319-323
Main Authors: Ciccone, A, Gatti, A, Melis, M, Cossu, G, Boncoraglio, G, Carriero, M R, Iurlaro, S, Agostoni, E
Format: Article
Language:English
Subjects:
Adolescent
Adult
Case-Control Studies
Cigarette smoking
Contraceptives, Oral - adverse effects
Female
Humans
Interviews as Topic - methods
Middle Aged
Neurological complications
Neurology
Neurosciences
Odds Ratio
Oral contraceptives
Retrospective Studies
Risk
Risk Factors
Sinus Thrombosis, Intracranial - chemically induced
Sinus Thrombosis, Intracranial - epidemiology
Smoking
Smoking - epidemiology
Thrombosis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Idiopathic cerebral sinus thrombosis (CST) can cause death and serious neurological disability. It is unknown whether smoking, a major risk factor for arterial stroke, is a risk factor also for CST. This work explored the association between smoking and CST in a hospital-based, multicentric, case-control study. In order to avoid the confounding effect of the different risk factors for CST, we analysed the homogeneous subgroup of oral contraceptive users. We compared the prevalence of smoking in a group of 43 young women with CST (cases), whose oral contraceptive use was the only known risk factor, with a sample of 255 healthy contraceptive users of similar age (controls). The prevalence of smoking in cases and controls was similar (26% vs. 29%). The age and geographic area-adjusted odds ratio was 0.9; 95% confidence interval, 0.4-1.8; p=0.7. Smoking in oral contraceptive users does not appear to be associated with CST.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-005-0507-5