Therapeutic effects of Probiotic Ointment for Atopic Dermatitis

The human microbiome is an integral part of the body, playing a crucial role in metabolism, energy homeostasis, the regulation of the immune system, and others. The study aims to examine the effect of probiotic ointment on the qualitative composition of the lesional skin microbiome in patients with...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2021-11, Vol.14 (11), p.6041-6048
Main Authors: Kasatkin, Mikhail, Smirnova, Lyudmila, Babaskin, Dmitrii
Format: Article
Language:English
Subjects:
Bacteria
Brain research
Dermatitis
Eczema
Edema
Erythema
Homeostasis
Immune system
Inflammatory bowel disease
Mental disorders
Microbiota
Microorganisms
Probiotics
Remission (Medicine)
Skin
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Summary:The human microbiome is an integral part of the body, playing a crucial role in metabolism, energy homeostasis, the regulation of the immune system, and others. The study aims to examine the effect of probiotic ointment on the qualitative composition of the lesional skin microbiome in patients with atopic dermatitis. The study population consisted of 110 patients aged 20 to 45 years with mild atopic dermatitis (AD). The patients were divided into two groups. One group received four different medications: levocetirizine dihydrochloride, enterosgel, topical Tizol gel, and topical 1% hydrocortisone ointment. The other group received a similar treatment with four different medications: levocetirizine dihydrochloride, enterosgel, topical Tizol gel, and topical probiotic ointment. The treatment period was one month. After treatment, the frequency and intensity of the main AD symptoms significantly decreased. A load of S. aureus fell in the probiotic-treated group from 73.4% to 29.1% (p
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2021.01050