4CPS-167 Sodium and magnesium alterations in the critical patient with SARS-CoV-2 and parenteral nutrition

• Published in: European journal of hospital pharmacy. Science and practice 2022-03, Vol.29 (Suppl 1), p.A85-A85
• Main Authors: Gonzalez Fernandez, A, Ibañez Carrillo, M, Guillen Martinez, O, Murcia Lopez, AC, Matoses Chirivella, C, Navarro Ruiz, A
• Format: Article
• Language: English
• Subjects: Conflicts of interest; Hypernatremia; Parenteral nutrition; Section 4: Clinical pharmacy services; Severe acute respiratory syndrome coronavirus 2; Sodium; Ventilators
• ISSN: 2047-9956; 2047-9964
• DOI: 10.1136/ejhpharm-2022-eahp.178

Background and importanceSevere SARS-CoV-2 infection requiring management in the critical care unit (CCU) involves long hospital stays with the need for artificial nutritional support and sometimes, depending on the clinical course, parenteral nutrition (PN).Aim and objectivesThe aim of this study was to analyse sodium and magnesium electrolyte disturbances associated with mechanical ventilation in critically ill patients with COVID-19 requiring PN.Material and methodsRetrospective observational study including 50 patients with SARS-CoV-2 admitted to CCU for 4 months (January–April 2021) who required PN.We analysed the variables of sex and age and the analytical values of sodium and magnesium during PN supplementation, as well as the contribution of these ions during PN supplementation. Na and Mg iones were not supplemented in PN, in patients with high levels.ResultsAge: average 67 years. Sex: 62% male; 38% female. Died: 54%. The results obtained are shown in table 1.Abstract 4CPS-167 Table 1Sodium and magnesium alterations, before and during the PN supplementation46% of patients had hypermagnesaemia at the start of PN, and about 30% started with hypernatraemia; in both cases it was maintained throughout the period of PN.Of the total number of patients, 5 developed hypermagnesaemia and 3 hypernatraemia during PN supplementationConclusion and relevanceCritically ill patients with SARS-CoV-2 had a high percentage of sodium and magnesium levels, 32% and 46%, respectively, at the time of starting PN, mainly associated with the use of mechanical ventilation. These alterations continued during PN supplementation in most cases.References and/or acknowledgementsConflict of interestNo conflict of interest