Update in diagnosis and management of interstitial lung disease

The field of interstitial lung disease (ILD) has undergone significant evolution in recent years, with an increasing incidence and more complex, ever expanding disease classification. In their most severe forms, these diseases lead to progressive loss of lung function, respiratory failure and eventu...

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Bibliographic Details
Published in:Clinical medicine (London, England) England), 2016-12, Vol.16 (6), p.s71-s78
Main Authors: Mikolasch, Theresia A, Garthwaite, Helen S, Porter, Joanna C
Format: Article
Language:English
Subjects:
Biopsy
Connective tissue diseases
Cryoscopic lung biopsy
idiopathic pulmonary fibrosis
Inflammation
interstitial lung disease
Lavage
Lung diseases
Medical prognosis
Pathogenesis
Patients
Pneumonia
Precision medicine
Pulmonary fibrosis
Tomography
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Summary:The field of interstitial lung disease (ILD) has undergone significant evolution in recent years, with an increasing incidence and more complex, ever expanding disease classification. In their most severe forms, these diseases lead to progressive loss of lung function, respiratory failure and eventually death. Despite notable advances, progress has been challenged by a poor understanding of pathological mechanisms and patient heterogeneity, including variable progression. The diagnostic pathway is thus being continually refined, with the introduction of tools such as transbronchial cryo lung biopsy and a move towards genetically aided, precision medicine. In this review, we focus on how to approach a patient with ILD and the diagnostic process.
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmedicine.16-6-s71