Sarcopenia in patients with type 2 diabetes mellitus: a case–control study in Maracaibo city, Venezuela

• Published in: International journal of diabetes in developing countries 2022-04, Vol.42 (2), p.203-210
• Main Authors: Pineda, Onofre, Stepenka, Victoria, Rivas-Motenegro, Alejandra, Villasmil-Hernandez, Nelson, Añez, Roberto, Salazar, Juan
• Format: Article
• Language: English
• Subjects: Diabetes; Diabetes mellitus (non-insulin dependent); Family Medicine; General Practice; Health Administration; Medicine; Medicine & Public Health; Metabolism; Multivariate analysis; Muscle strength; Original Article; Sarcopenia; Sex ratio; Skeletal muscle
• ISSN: 0973-3930; 1998-3832
• DOI: 10.1007/s13410-021-00989-7

Background/purpose of the study Several studies implicate skeletal muscle as a physio-pathological target among the metabolic disturbances of diabetes, or with the mechanisms shared by sarcopenia and type 2 diabetes mellitus (T2DM). The present study aimed to determine the relationship between sarcopenia and T2DM in outpatients of the Zulian Diabetes Institute, Maracaibo, Venezuela. Methods A case–control study was performed on patients diagnosed with T2DM that went to the Zulian Diabetes Institute between January and June 2019. After obtaining a final sample of 131 patients with T2DM, control subjects were selected in a 1:1 ratio according to sex. The European Working Group on Sarcopenia in Older People (EWGSOP) criteria were followed to diagnose sarcopenia, so muscle mass, muscle strength, and muscle performance were determined. Results A total of 261 patients were evaluated (131 with T2DM and 131 controls), with no differences in mean age (with T2DM 63.6 ± 9.3 vs. controls 63.6 ± 9.4 years old; p  = 0.99). The prevalence of sarcopenia in control subjects was 9.9% and in subjects with diabetes 25.2%; p