Dietary poly‐β‐hydroxybutyrate supplementation can effectively improve growth, digestive enzyme activities, immune‐related gene expression, disease resistance, and intestinal mucosal barrier of gibel carp, Carassius auratus gibelio

• Published in: Journal of the World Aquaculture Society 2022-08, Vol.53 (4), p.816-835
• Main Authors: Liu, Yang, Chen, Peng, Wang, Zisheng, Lv, Tingli, Li, Xiaoxia, Tian, Hongyan, Zhang, Yichan, Cang, Pingping, Chi, Shuang, Sun, Yuyu, Qiao, Guo
• Format: Article
• Language: English
• Subjects: Aquatic animals; Bacterial diseases; Carassius auratus gibelio; Carp; Carp culture; Disease resistance; Enzymatic activity; Enzyme activity; Enzymes; Feed additives; Fish; Freshwater fishes; Gene expression; Growth; Immune response; Immunity; intestinal mucosal barrier; Intestine; Mucosa; poly‐β‐hydroxybutyrate (PHB); prebiotics
• ISSN: 0893-8849; 1749-7345
• DOI: 10.1111/jwas.12900

Poly‐β‐hydroxybutyrate (PHB) can promote growth and enhance immunity of aquatic animals such as gibel carp, Carassius auratus gibelio. However, the optimal dietary supplementation level and feeding duration for gibel carp are still unclear. In this study, effects of various PHB supplementation levels on gibel carp growth performance, digestive enzyme activities, immune function, disease resistance, and intestinal mucosal barrier were evaluated. Six experimental diets differing in PHB levels were formulated, that is, 0% (P0 as control), 0.5% (P0.5), 1% (P1), 2% (P2), 4% (P4), and 8% (P8). Results indicated that PHB promoted fish growth performance significantly (p