Sticky logic toolkit programs cells to pattern

On page 324, Kim et at.1 report a way of using synthetic adhesins to form multicellular patterns that are visible to the naked eye - shedding light on the molecular mechanisms that might have driven the evolution of multicellular organisms. [...]they looked at how changing the binding affinity of th...

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Bibliographic Details
Published in:Nature (London) 2022-08, Vol.608 (7922), p.267-268
Main Author: Fernández, Luis Ángel
Format: Article
Language:English
Subjects:
Adhesins
Antigens
Biomedical materials
Biosensors
Biotechnology
Evolution
Growth rate
Interfaces
Microorganisms
Molecular modelling
Nanobodies
Synthetic biology
Online Access:Get full text
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Summary:On page 324, Kim et at.1 report a way of using synthetic adhesins to form multicellular patterns that are visible to the naked eye - shedding light on the molecular mechanisms that might have driven the evolution of multicellular organisms. [...]they looked at how changing the binding affinity of the nanobody-antigen pair affected the width of the interface, and how different bacterial growth rates changed the interface's curvature. Luis Ángel Fernández is in the Department of Microbial Biotechnology, National Centre for Biotechnology, Spanish National Research Council (CNB-CSIC), 28049 Madrid, Spain. e-mail: lafdez@cnb.csic.es The author declares no competing interests. 1.
ISSN:0028-0836
1476-4687
DOI:10.1038/d41586-022-02102-2