Application of diode lasers in light-oxygen cancer therapy

Singlet oxygen is the lowest energy electronic excited state of the oxygen molecule which is able to damage living cells. This property has long been used for the sensitized destruction of tumors in photodynamic cancer therapy. Here it is shown that similar results can be achieved without photosensi...

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Bibliographic Details
Published in:Semiconductors (Woodbury, N.Y.) N.Y.), 2014, Vol.48 (1), p.123-128
Main Authors: Zakharov, S. D., Korochkin, I. M., Yusupov, A. S., Bezotosnyi, V. V., Cheshev, E. A., Frantzen, F.
Format: Article
Language:English
Subjects:
2012
Absorption spectra
Active oxygen
Antimitotic agents
Antineoplastic agents
Cancer
Continuous radiation
Health aspects
Magnetic Materials
Magnetism
Materials of the 3rd Symposium “semiconductor Lasers: Physics and Technology” (St. Petersburg
October 13–16
Phototherapy
Physics
Physics and Astronomy
Semiconductor lasers
Singlet oxygen
Therapy
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Summary:Singlet oxygen is the lowest energy electronic excited state of the oxygen molecule which is able to damage living cells. This property has long been used for the sensitized destruction of tumors in photodynamic cancer therapy. Here it is shown that similar results can be achieved without photosensitizers by using the light-oxygen effect. High-power continuous-wave (cw) diode lasers emitting within the absorption bands of dissolved molecular oxygen are most appropriate for light-oxygen cancer therapy.
ISSN:1063-7826
1090-6479
DOI:10.1134/S1063782614010254