A New Lignan from the Leaves of Styrax annamensis

Phytochemical investigation of the ethyl acetate extract of Styrax annamensis leaves has led to the isolation and determination of a new lignan, 7R,8S,7′S,8′R-3,4,3′-trimethoxy-9,4′,7′-trihydroxy-8.8′,7.O.9′-lignan ( 1 ), together with a known compound, 4-ketopinoresinol ( 2 ). Compound 2 was isolat...

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Bibliographic Details
Published in:Chemistry of natural compounds 2022-07, Vol.58 (4), p.607-609
Main Authors: Tra, Nguyen Thanh, Thuy, Nguyen Ngoc Nhu, Van Tuyen, Nguyen, Ha, Nguyen Thi Thu, Anh, Le Thi Tu, Son, Ninh The
Format: Article
Language:English
Subjects:
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Ethyl acetate
Lignans
Medicine, Botanic
Medicine, Herbal
Organic Chemistry
Plant Sciences
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Summary:Phytochemical investigation of the ethyl acetate extract of Styrax annamensis leaves has led to the isolation and determination of a new lignan, 7R,8S,7′S,8′R-3,4,3′-trimethoxy-9,4′,7′-trihydroxy-8.8′,7.O.9′-lignan ( 1 ), together with a known compound, 4-ketopinoresinol ( 2 ). Compound 2 was isolated from the genus Styrax for the first time, and showed moderate activity to capture the DPPH radical with the IC 50 value of 56.74 ± 0.79 μg/mL.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03752-4