Polish clinical practice guideline on hyperthermic intraperitoneal chemotherapy (HIPEC) with cytoreductive surgery in peritoneal malignancy treatment

The management of peritoneal surface malignancy is a significant clinical problem in oncology. It was demonstrated that the combination of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) may lead to long-term control of the disease or improved survival in select...

Full description

Saved in:
Bibliographic Details
Published in:Current Gynecologic Oncology 2014-08, Vol.12 (2), p.86-97
Main Authors: Rutkowski, Piotr, Śpiewankiewicz, Beata, Herman, Krzysztof, Jastrzębski, Tomasz, Kładny, Józef, Kojs, Zbigniew, Krzakowski, Maciej, Polkowski, Wojciech, Wyrwicz, Lucjan, Wysocki, Piotr, Zdzienicki, Marcin, Zegarski, Wojciech
Format: Article
Language:eng ; pol
Subjects:
Cancer
Chemotherapy
Clinical practice guidelines
Gastric cancer
Metastasis
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The management of peritoneal surface malignancy is a significant clinical problem in oncology. It was demonstrated that the combination of complete cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) may lead to long-term control of the disease or improved survival in selected patients. The aim of this paper was to present the optimal indications and technical guidelines for performing HIPEC in Poland. The application of this method requires experience of a multidisciplinary team of physicians (gynecologic oncologist, surgeon and clinical oncologist), availability of diagnostic and therapeutic resources (intensive care unit) as well as a dedicated perfusion system. A crucial aspect for obtaining optimal treatment outcomes is the selection of patients. Such a selection takes place both at the beginning of treatment and intraoperatively. The initial selection of patients qualified for HIPEC includes ruling out extraperitoneal spread of cancer and metastases to the liver (single resectable liver metastases in patients with colorectal carcinoma are not contraindications) and lungs. According to current international guidelines, the HIPEC procedure is a standard treatment in patients with ovarian carcinoma that metastasizes to the peritoneum, in colorectal cancer, when PCI
ISSN:2081-1632
2081-1632
DOI:10.15557/CGO.2014.0009