Role of peritonectomy in cytoreductive surgery of ovarian cancer

Background: Global statistics indicate continuously increasing incidence of ovarian cancer. As the outcome of surgery- and chemotherapy-based therapies of this condition are highly unsatisfactory, the search is underway for novel surgical techniques, more effective drugs and new treatment protocols....

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Bibliographic Details
Published in:Current Gynecologic Oncology 2009-01, Vol.7 (2), p.107
Main Authors: Soja, Paweł, Sałek, Agata, Dudka, Paweł, Naróg, Maciej, Skręt-Magierło, Joanna, Raba, Grzegorz, Kluza, Roman, Skręt, Andrzej
Format: Article
Language:eng ; pol
Subjects:
Chemotherapy
Medical libraries
Ovarian cancer
Surgery
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Summary:Background: Global statistics indicate continuously increasing incidence of ovarian cancer. As the outcome of surgery- and chemotherapy-based therapies of this condition are highly unsatisfactory, the search is underway for novel surgical techniques, more effective drugs and new treatment protocols. Peritonectomy is a technique enabling a more complete cytoreduction and better survival indices. The aim of this paper is to review current literature related to peritonectomy – a novel technique in cytoreductive surgery of ovarian cancer. Material and method: Internet-based search of medical libraries (Cochrane, PubMed and Medline) using such key words as: “ovarian”, “cancer”, “chemotherapy”, “peritonectomy”, “chemohyperthermia”, and various combinations thereof. The review encompassed papers published after 1990. Results: Literature data enable an insight into several techniques of peritonectomy, as well as its combination with intraperitoneal hyperthermic chemotherapy. Results of surgical treatment including peritonectomy and complications on the part of other organs as sequels of this procedure are reviewed. Conclusions: Peritonectomy is a novel surgical technique, which may contribute to improvement of outcome of ovarian cancer treatment. Although this type of procedure is associated with an increased risk of complications due to its greater invasiveness, in most authors’ opinion complication and mortality rates are acceptable. Based on available literature we may conclude that prospective studies are necessary in order to determine the role of this technique in the aspects of survival and postoperative complication rates.
ISSN:2081-1632