Alterations of Microorganisms in Tongue Coating of Gastric Precancerous Lesion Patients with a Damp Phlegm Pattern

Objective. In the research, the microbial changes in the tongue coating of patients with a damp phlegm pattern of gastric precancerous lesion (GPL) were investigated. Methods. This was a case-control study, in which 80 tongue coating samples were collected including 40 patients with a damp phlegm pa...

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Bibliographic Details
Published in:BioMed research international 2022-09, Vol.2022, p.1-14
Main Authors: Xiao, Xiangqun, Zhang, Renling, Lu, Junhong, Xu, Yifeng, Zhu, Zhujing, Wang, Yiqin, Shi, Yaxiang, Hao, Yiming
Format: Article
Language:English
Subjects:
Abundance
Antibiotics
Biofilms
Blood
Cancer
Causes of
Chinese medicine
Coating
Coatings
Complications and side effects
Composition
Development and progression
Disease
Excretory system
Experimental methods
Gastric cancer
Gastrointestinal tumors
Health aspects
Infectious diseases
Lesions
Metabolites
Microbial mats
Microbiology
Microbiomes
Microorganisms
Mouth
Oncology, Experimental
Oral manifestations of general diseases
Patients
Phenotypes
Precancerous conditions
Probiotics
Relative abundance
Research methodology
rRNA 16S
Tongue
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Summary:Objective. In the research, the microbial changes in the tongue coating of patients with a damp phlegm pattern of gastric precancerous lesion (GPL) were investigated. Methods. This was a case-control study, in which 80 tongue coating samples were collected including 40 patients with a damp phlegm pattern of GPL, 20 patients with a nondamp phlegm pattern of GPL, and 20 healthy control people. The 16S rRNA microbiome technology was used to analyze the alterations of microorganisms in tongue coating of GPL patients with a damp phlegm pattern. Results. Microorganisms in the genus level were analyzed. Compared with the healthy control group, the relative abundance of 4 microorganisms (Solobacterium, Rothia, Oribacterium, and Alloprevotella) in the GPL group was significantly higher (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2022/7210909