Candida glabrata

[...]meropenem was switched to cefuroxime. Risk factors for candiduria in our case included urinary catheterisation, intensive care unit stay, use of broad-spectrum antibiotics, female sex, and prior surgery.2 The placental remnants in our case induced infection and septicaemia. Compared with other...

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Published in:Hong Kong medical journal = Xianggang yi xue za zhi 2022-08, Vol.28 (4), p.324
Main Authors: Wong, C K, Cho, L Y, Lau, W L, Cheung, Ingrid YY, Yu, Chloe HT, Leung, W C
Format: Article
Language:chi ; eng
Subjects:
Antibiotics
Bladder
Fistula
Infectious diseases
Intensive care
Placenta
Sepsis
Surgery
Tomography
Ulcers
Ultrasonic imaging
Urinary tract diseases
Urinary tract infections
Urine
Urogenital system
Vagina
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Summary:[...]meropenem was switched to cefuroxime. Risk factors for candiduria in our case included urinary catheterisation, intensive care unit stay, use of broad-spectrum antibiotics, female sex, and prior surgery.2 The placental remnants in our case induced infection and septicaemia. Compared with other Candida species, manyC glabrata isolates are resistant to azoles due to efflux pump[-]mediated resistance, genetic alterations under stress and biofilm protection.4 A study in the United States revealed that 14% of C glabrata isolates were resistant to fluconazole.5 The presence of fungus ball/fungal bezoars in urinary tract infection is extremely rare in adults. According to treatment guidelines of the Infectious Diseases Society of America, removal of the obstructing mycelial mass by surgical or endoscopic means is strongly recommended.6 Although culture results revealed that the C glabrata was susceptible-dose-dependent to fluconazole, use of fluconazole alone was likely to be insufficient due to the fungal ball in the bladder.
ISSN:1024-2708
2226-8707
DOI:10.12809/hkmj219449