Retroperitoneal Leiomyosarcoma Masquerading as Renal Cell Carcinoma—a Diagnostic Dilemma

Leiomyosarcoma of soft tissue is relatively a rare neoplasm and the third most common retroperitoneal sarcoma with highly aggressive nature. Most of it shows a female predominance. Here we present a case of 51 year old male with retroperitoneal swelling involving left kidney. Gross examination revea...

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Bibliographic Details
Published in:Indian journal of surgery 2022-10, Vol.84 (5), p.1101-1102
Main Authors: Sikdar, Neha, Subramanian, Kalaivani Selvi, Ivan, Erli Amel, Maruthavanan
Format: Article
Language:English
Subjects:
Carcinoma, Renal cell
Cardiac Surgery
Images in Surgery
Kidney cancer
Leiomyosarcoma
Medicine
Medicine & Public Health
Muscle proteins
Neurosurgery
Pediatric Surgery
Plastic Surgery
Surgery
Thoracic Surgery
Tumors
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Summary:Leiomyosarcoma of soft tissue is relatively a rare neoplasm and the third most common retroperitoneal sarcoma with highly aggressive nature. Most of it shows a female predominance. Here we present a case of 51 year old male with retroperitoneal swelling involving left kidney. Gross examination revealed a tumour that appeared arising from the renal cortex. Cut surface of which showed variegated appearance with yellowish areas and cystic changes mimicking renal cell carcinoma. Histopathologically it was diagnosed as high grade leiomyosarcoma infiltrating the adjacent renal cortex and the ureter. Immunohistochemically, the tumor cells were diffusely positive for smooth muscle actin (SMA). This is a rare case of retroperitoneal leiomyosarcoma with renal and ureteric infiltration.
ISSN:0972-2068
0973-9793
DOI:10.1007/s12262-021-03129-x