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Frequency of Hepatitis C Virus and Human Immunodeficiency Virus Coinfection among Intravenous Drug Abusers; Experience from A Single Rehabilitation Center
Objectives: To determine the frequency of Hepatitis C virus and Human Immunodeficiency Virus (HIV) Coinfection among Intravenous drug abusers in a rehabilitation Centre. Study Design: Cross-sectional analytical study. Place and Duration of Study: Medical and Rehabilitation Centre of District Jail, L...
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Published in: | Pakistan Armed Forces medical journal 2022-08, Vol.72 (4), p.1219-23 |
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container_title | Pakistan Armed Forces medical journal |
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creator | Saeed, Khawar Khan, Asadullah Khanam, Afshan Lashari, Naveed Aslam Khan, Hajra Khan, Ahsan |
description | Objectives: To determine the frequency of Hepatitis C virus and Human Immunodeficiency Virus (HIV) Coinfection among Intravenous drug abusers in a rehabilitation Centre.
Study Design: Cross-sectional analytical study.
Place and Duration of Study: Medical and Rehabilitation Centre of District Jail, Lahore Pakistan, from Jul to Dec 2019.
Methodology: A total of 220 participants with a history of intravenous drug abuse were screened for Human immunodeficiency virus, Hepatitis C virus, and hepatitis B virus, with positive cases confirmed by polymerase chain reaction tests.
Results: The median was age 27(8.0) years. Only 12 (5.5) had above higher secondary education. Injectable heroin and metamphetamine used by the respondents were 182 (82.7) and 41 (22.5), respectively. Human immunodeficiency virus infection was present in 163 (74.1), Hepatitis C infection in 149 (67.7), Hepatitis B infection in 9 (4.09), and co-infection of human immunodeficiency and hepatitis C virus infections in 118 (53.6) respectively. Human immunodeficiency virus infection showed a significant association with education level (p |
doi_str_mv | 10.51253/pafmj.v72i4.4122 |
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Study Design: Cross-sectional analytical study.
Place and Duration of Study: Medical and Rehabilitation Centre of District Jail, Lahore Pakistan, from Jul to Dec 2019.
Methodology: A total of 220 participants with a history of intravenous drug abuse were screened for Human immunodeficiency virus, Hepatitis C virus, and hepatitis B virus, with positive cases confirmed by polymerase chain reaction tests.
Results: The median was age 27(8.0) years. Only 12 (5.5) had above higher secondary education. Injectable heroin and metamphetamine used by the respondents were 182 (82.7) and 41 (22.5), respectively. Human immunodeficiency virus infection was present in 163 (74.1), Hepatitis C infection in 149 (67.7), Hepatitis B infection in 9 (4.09), and co-infection of human immunodeficiency and hepatitis C virus infections in 118 (53.6) respectively. Human immunodeficiency virus infection showed a significant association with education level (p<0.01) and drug use (p=0.01). Hepatitis C infection showed association with marital status (p=0.04), religion (p<0.01) and drugs used, while Co-infection showed association with religion and drug used (p=0.01 and p=0.004 respectively).
Conclusion: Intravenous drug users have a significantly higher prevalence of Human immunodeficiency and hepatitis C infection and their co-infection, occurring in more than half of injectable users. In addition, these infections show significant association with education status, marital status and type of injectable drug used.</description><identifier>ISSN: 0030-9648</identifier><identifier>EISSN: 2411-8842</identifier><identifier>DOI: 10.51253/pafmj.v72i4.4122</identifier><language>eng</language><publisher>Rawalpindi: Knowledge Bylanes</publisher><subject>Addictions ; Bacterial infections ; Comorbidity ; Demographics ; Drug addicts ; Drug therapy ; Health aspects ; Hepatitis B ; Hepatitis C ; Hepatitis C virus ; HIV (Viruses) ; Infection ; Marital status ; Opium trade ; Viral infections</subject><ispartof>Pakistan Armed Forces medical journal, 2022-08, Vol.72 (4), p.1219-23</ispartof><rights>COPYRIGHT 2022 Knowledge Bylanes</rights><rights>(c)2022 Pakistan Armed Forces Medical Journal</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2729874966/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2729874966?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,25753,27924,27925,37012,44590,75126</link.rule.ids></links><search><creatorcontrib>Saeed, Khawar</creatorcontrib><creatorcontrib>Khan, Asadullah</creatorcontrib><creatorcontrib>Khanam, Afshan</creatorcontrib><creatorcontrib>Lashari, Naveed Aslam</creatorcontrib><creatorcontrib>Khan, Hajra</creatorcontrib><creatorcontrib>Khan, Ahsan</creatorcontrib><title>Frequency of Hepatitis C Virus and Human Immunodeficiency Virus Coinfection among Intravenous Drug Abusers; Experience from A Single Rehabilitation Center</title><title>Pakistan Armed Forces medical journal</title><description>Objectives: To determine the frequency of Hepatitis C virus and Human Immunodeficiency Virus (HIV) Coinfection among Intravenous drug abusers in a rehabilitation Centre.
Study Design: Cross-sectional analytical study.
Place and Duration of Study: Medical and Rehabilitation Centre of District Jail, Lahore Pakistan, from Jul to Dec 2019.
Methodology: A total of 220 participants with a history of intravenous drug abuse were screened for Human immunodeficiency virus, Hepatitis C virus, and hepatitis B virus, with positive cases confirmed by polymerase chain reaction tests.
Results: The median was age 27(8.0) years. Only 12 (5.5) had above higher secondary education. Injectable heroin and metamphetamine used by the respondents were 182 (82.7) and 41 (22.5), respectively. Human immunodeficiency virus infection was present in 163 (74.1), Hepatitis C infection in 149 (67.7), Hepatitis B infection in 9 (4.09), and co-infection of human immunodeficiency and hepatitis C virus infections in 118 (53.6) respectively. Human immunodeficiency virus infection showed a significant association with education level (p<0.01) and drug use (p=0.01). Hepatitis C infection showed association with marital status (p=0.04), religion (p<0.01) and drugs used, while Co-infection showed association with religion and drug used (p=0.01 and p=0.004 respectively).
Conclusion: Intravenous drug users have a significantly higher prevalence of Human immunodeficiency and hepatitis C infection and their co-infection, occurring in more than half of injectable users. In addition, these infections show significant association with education status, marital status and type of injectable drug used.</description><subject>Addictions</subject><subject>Bacterial infections</subject><subject>Comorbidity</subject><subject>Demographics</subject><subject>Drug addicts</subject><subject>Drug therapy</subject><subject>Health aspects</subject><subject>Hepatitis B</subject><subject>Hepatitis C</subject><subject>Hepatitis C virus</subject><subject>HIV (Viruses)</subject><subject>Infection</subject><subject>Marital status</subject><subject>Opium trade</subject><subject>Viral infections</subject><issn>0030-9648</issn><issn>2411-8842</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNptkd1q3DAQhU1poEuSB-idoNfe6s-Sll4tbtJdCASa0Fshy-OtlpXkSnZoXqVPG8UbKIVqQIKZ74yYOVX1keB1Q2jDPo9m8Mf1k6SOrzmh9F21opyQWilO31crjBmuN4KrD9V1zkdcTsMox82q-nOb4NcMwT6jOKAdjGZyk8uoRT9cmjMyoUe72ZuA9t7PIfYwOOsW_gy00YUB7ORiQMbHcED7MCXzBCGW6tc0H9C2mzOk_AXd_B4hvYoBDSl6tEUPLhxOgL7DT9O5k5vM0qeFMEG6qi4Gc8pw_fZeVo-3N4_trr67_7Zvt3e1pVhOtcRGbYgBxoSQSlGjetGAAtGUsrHQsHIzKntLqexIB7JpOBHdwBQTHNhl9encdkyxbCJP-hjnFMqPmkq6UZJvhPhLHcwJdBk5liGtd9nqraScU0wEKdT6P1SJHryzMZTllfw_AnIW2BRzTjDoMTlv0rMmWC_e6sVbvXirX71lL4lHmSY</recordid><startdate>20220831</startdate><enddate>20220831</enddate><creator>Saeed, Khawar</creator><creator>Khan, Asadullah</creator><creator>Khanam, Afshan</creator><creator>Lashari, Naveed Aslam</creator><creator>Khan, Hajra</creator><creator>Khan, Ahsan</creator><general>Knowledge Bylanes</general><general>AsiaNet Pakistan (Pvt) Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20220831</creationdate><title>Frequency of Hepatitis C Virus and Human Immunodeficiency Virus Coinfection among Intravenous Drug Abusers; Experience from A Single Rehabilitation Center</title><author>Saeed, Khawar ; Khan, Asadullah ; Khanam, Afshan ; Lashari, Naveed Aslam ; Khan, Hajra ; Khan, Ahsan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c207t-70a891ae33667882a8d65e8e65207ace537ac327dc227b1be755416bf38364e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Addictions</topic><topic>Bacterial infections</topic><topic>Comorbidity</topic><topic>Demographics</topic><topic>Drug addicts</topic><topic>Drug therapy</topic><topic>Health aspects</topic><topic>Hepatitis B</topic><topic>Hepatitis C</topic><topic>Hepatitis C virus</topic><topic>HIV (Viruses)</topic><topic>Infection</topic><topic>Marital status</topic><topic>Opium trade</topic><topic>Viral infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saeed, Khawar</creatorcontrib><creatorcontrib>Khan, Asadullah</creatorcontrib><creatorcontrib>Khanam, Afshan</creatorcontrib><creatorcontrib>Lashari, Naveed Aslam</creatorcontrib><creatorcontrib>Khan, Hajra</creatorcontrib><creatorcontrib>Khan, Ahsan</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Pakistan Armed Forces medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saeed, Khawar</au><au>Khan, Asadullah</au><au>Khanam, Afshan</au><au>Lashari, Naveed Aslam</au><au>Khan, Hajra</au><au>Khan, Ahsan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frequency of Hepatitis C Virus and Human Immunodeficiency Virus Coinfection among Intravenous Drug Abusers; Experience from A Single Rehabilitation Center</atitle><jtitle>Pakistan Armed Forces medical journal</jtitle><date>2022-08-31</date><risdate>2022</risdate><volume>72</volume><issue>4</issue><spage>1219</spage><epage>23</epage><pages>1219-23</pages><issn>0030-9648</issn><eissn>2411-8842</eissn><abstract>Objectives: To determine the frequency of Hepatitis C virus and Human Immunodeficiency Virus (HIV) Coinfection among Intravenous drug abusers in a rehabilitation Centre.
Study Design: Cross-sectional analytical study.
Place and Duration of Study: Medical and Rehabilitation Centre of District Jail, Lahore Pakistan, from Jul to Dec 2019.
Methodology: A total of 220 participants with a history of intravenous drug abuse were screened for Human immunodeficiency virus, Hepatitis C virus, and hepatitis B virus, with positive cases confirmed by polymerase chain reaction tests.
Results: The median was age 27(8.0) years. Only 12 (5.5) had above higher secondary education. Injectable heroin and metamphetamine used by the respondents were 182 (82.7) and 41 (22.5), respectively. Human immunodeficiency virus infection was present in 163 (74.1), Hepatitis C infection in 149 (67.7), Hepatitis B infection in 9 (4.09), and co-infection of human immunodeficiency and hepatitis C virus infections in 118 (53.6) respectively. Human immunodeficiency virus infection showed a significant association with education level (p<0.01) and drug use (p=0.01). Hepatitis C infection showed association with marital status (p=0.04), religion (p<0.01) and drugs used, while Co-infection showed association with religion and drug used (p=0.01 and p=0.004 respectively).
Conclusion: Intravenous drug users have a significantly higher prevalence of Human immunodeficiency and hepatitis C infection and their co-infection, occurring in more than half of injectable users. In addition, these infections show significant association with education status, marital status and type of injectable drug used.</abstract><cop>Rawalpindi</cop><pub>Knowledge Bylanes</pub><doi>10.51253/pafmj.v72i4.4122</doi><tpages>-1195</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Addictions Bacterial infections Comorbidity Demographics Drug addicts Drug therapy Health aspects Hepatitis B Hepatitis C Hepatitis C virus HIV (Viruses) Infection Marital status Opium trade Viral infections |
title | Frequency of Hepatitis C Virus and Human Immunodeficiency Virus Coinfection among Intravenous Drug Abusers; Experience from A Single Rehabilitation Center |
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