Influencing Factors for Complication with Aneurysm Rupture of the Fetal Posterior Communicating Artery After Clipping Through the Lateral Supraorbital Approach and Prognosis

• Published in: Artery research 2021-12, Vol.27 (4), p.186-193
• Main Authors: Chen, Yunxiang, Cai, Yurong, Chen, Huahui, Lin, Xiafeng, Zhou, Gezhi, Yuan, Jianlie, Fan, Yuejun
• Format: Article
• Language: English
• Subjects: Aneurysms; Carotid arteries; Cerebrospinal fluid; Disability; Headaches; Hematoma; Hemorrhage; Hydrocephalus; Hypertension; Medical imaging; Medicine; Medicine & Public Health; Nomograms; Research Article; Software; Statistical analysis; Veins & arteries
• ISSN: 1876-4401; 1872-9312; 1876-4401
• DOI: 10.1007/s44200-021-00007-5

Background To explore the influencing factors for complication with aneurysm rupture of the fetal posterior communicating artery after clipping through the lateral supraorbital (LSO) approach and prognosis. Methods A total of 119 patients with posterior communicating artery aneurysm (PCoAA) accompanied by fetal posterior cerebral artery (fPCA), who underwent clipping through the LSO approach from January 2014 to December 2019, were selected. They were aged 50–70 years old, (60.5 ± 13.7) on average. The treatment outcome, incidence of complications and follow-up results were analyzed. Based on the follow-up results, univariate comparative analysis was conducted for the clinical data of patients with good or poor prognosis. The statistically significant factors were incorporated into multivariate Cox regression analysis, and the nomogram prediction model for prognosis was established. The accuracy of the model was assessed using the Hosmer–Lemeshow goodness-of-fit test. Results Clipping through the LSO approach was successful in all cases. Perioperative complications occurred in 41 patients. According to the follow-up results, 89 patients had good prognosis, while 30 had poor prognosis. Age of > 65 years old, history of hypertension, high Hunt–Hess grade and high modified Fisher grade were independent risk factors for the poor prognosis of patients with PCoAA accompanied by fPCA after clipping through the LSO approach. The results obtained by the established model were consistent with the actual ones. Conclusion Age, history of hypertension, Hunt–Hess grade and modified Fisher grade are independent risk factors for the prognosis of patients with PCoAA accompanied by fPCA after clipping through the LSO approach.