Biomedical applications of microfluidic devices: Achievements and challenges

There has been a recent interest in microfluidics due to their wide application and unique integration of concepts, including physics, materials science, chemistry, microelectronics, and biology. Microfluidic chips can be applied in different fields, particularly in the biomedical sector, such as dr...

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Bibliographic Details
Published in:Polymers for advanced technologies 2022-12, Vol.33 (12), p.3920-3934
Main Authors: Akbari Kenari, Mahsa, Rezvani Ghomi, Erfan, Akbari Kenari, Amirreza, Arabi, Seyed Mohammad Saeed, Deylami, Javad, Ramakrishna, Seeram
Format: Article
Language:English
Subjects:
biomaterial
Biomedical materials
drug delivery
Materials science
microfluidic device
Microfluidic devices
Microfluidics
organ‐on‐chip
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Summary:There has been a recent interest in microfluidics due to their wide application and unique integration of concepts, including physics, materials science, chemistry, microelectronics, and biology. Microfluidic chips can be applied in different fields, particularly in the biomedical sector, such as drug delivery, diagnosis devices, cell culture, and scaffold fabrication. Various materials, including metals, polymers, and ceramics, can be manufactured into microscale chips with channels and chambers. Platforms of any required size, structure, or geometry can be fabricated using a wide range of fabrication techniques, for example, three‐dimensional printing. This manuscript assesses the microfluidic devices starting from their historical development, materials, fabrication methods and challenges, as well as biomedical applications.
ISSN:1042-7147
1099-1581
DOI:10.1002/pat.5847