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Expecting the Unexpected: an Encounter with Primary Neuroendocrine Cancer of the Breast

Primary neuroendocrine carcinoma of the breast (NECB) is a rare disease with an incidence of approximately 1–5%. The World Health Organization classified them as a separate subtype of breast carcinoma. It is often confused with neuroendocrine differentiation of an invasive ductal carcinoma which may...

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Bibliographic Details
Published in:Indian journal of surgery 2022-10, Vol.84 (Suppl 3), p.816-819
Main Authors: Basu, Shouptik, Mukherjee, Ramanuj
Format: Article
Language:English
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Summary:Primary neuroendocrine carcinoma of the breast (NECB) is a rare disease with an incidence of approximately 1–5%. The World Health Organization classified them as a separate subtype of breast carcinoma. It is often confused with neuroendocrine differentiation of an invasive ductal carcinoma which may lead to an erroneous management, since there are yet no strict management guidelines, for this histological subtype. Due to its histological uniqueness and bizarre biological behaviour, certain subtypes of these cancers are often have a sinister prognosis. We report a single case of a primary small cell carcinoma, a variant of neuroendocrine carcinoma of the breast (NECB) which was managed by with mastectomy and adjuvant chemotherapy.
ISSN:0972-2068
0973-9793
DOI:10.1007/s12262-021-02954-4