Effects of excessive urea on rumen morphology and microbiota in Jianzhou Da'er goat (Capra hircus)

Urea is frequently used as a protein supplement in ruminant diets, but if used improperly, it can easily result in urea poisoning. The purpose of this study was to explore the effects of excessive urea feeding on rumen pathology and microbial diversity of the Jianzhou Da'er goat (Capra hircus)....

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Bibliographic Details
Published in:Research in veterinary science 2022-12, Vol.153, p.1-7
Main Authors: Zhang, Nanchi, Zhang, Hua, Ding, Junren, Wang, Li, Wei, Yong, Xiang, Yi
Format: Article
Language:English
Subjects:
Ammonia
Bacteria
Capra hircus
Decomposition
Dry matter
Experiments
Goats
Histopathology
Jianzhou Da'er goat
Microbial diversity
Microbiota
Microorganisms
Morphology
Nitrogen
Pigments
Poisoning
Prevotella ruminicola
rRNA 16S
Rumen
Rumen microorganisms
Ruminobacter amylophilus
Sequence analysis
Staining
Stratum corneum
Urea
Urea poisoning
Veterinary medicine
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Summary:Urea is frequently used as a protein supplement in ruminant diets, but if used improperly, it can easily result in urea poisoning. The purpose of this study was to explore the effects of excessive urea feeding on rumen pathology and microbial diversity of the Jianzhou Da'er goat (Capra hircus). In this study, 9 male Jianzhou Da'er goats with an average weight of 22.9 kg were randomly divided into the control group (0% urea), 5% urea group and 10% urea group (dry matter basis, 3 goats per group). Morphological differences of rumen tissues were analyzed by Hematoxylin-Eosin staining and Prussian blue staining, and rumen microorganisms differences were analyzed by 16S rDNA sequencing on the Illumina Novaseq platform. Histopathological analysis showed that the length of rumen papilla in the 5% urea and 10% urea groups were shortened compared to the control group, and the thickness of the stratum corneum and muscular layer were significantly thinned (P 
ISSN:0034-5288
1532-2661
DOI:10.1016/j.rvsc.2022.10.009