Topological Co-indices of Hydroxyethyl Starch Conjugated with Hydroxychloroquine Used for COVID-19 Treatment

• Published in: Polycyclic aromatic compounds 2022-11, Vol.42 (10), p.7130-7142
• Main Authors: Yang, Jun, Muhammad, Mehwish Hussain, Siddiqui, Muhammad Kamran, Hanif, Muhammad Farhan, Nasir, Muhammad, Ali, Safdar, Liu, Jia-Bao
• Format: Article
• Language: English
• Subjects: Chemical properties; Chloroquine; Computer applications; corona virus disease 2019; Coronaviruses; COVID-19; Disease transmission; Expectancy; Forgotten co-index; Hydroxychloroquine; Hydroxyethyl starch; Hydroxyethyl starch with Hydroxychloroquine conjugate; Molecular structure; multiplicative co-index; Pandemics; Scientists; Topological co-index; Topology; Viruses
• ISSN: 1040-6638; 1563-5333
• DOI: 10.1080/10406638.2021.1996407

In the era of 2019 the most dangerous disease that have affected more than 200 countries is Covid-19 (i.e. corona virus disease 2019) spread by the virus (i.e. novel coronavirus) which is transmitted from susceptible person to survivors in his surroundings. Such an epidemicity occurs first time in the world and number of cases are in excess of normal expectancy for the different areas that's why it is not easy to overcome this pandemic circumstances immediately. However, it is a challenge to develop anti-virus drugs for the suspected patients at global level. The scientists are interested in detailed experiments on Chloroquine (CQ) and Hydroxychloroquine (HCQ) as one of the unique substance used in the manufacturing for an anti virus drugs. For instance the Hydroxychloroquine conjugated molecular structure became an interesting chemical by the scientist. The significance of both substances can be examine by the number of publications which are leading us to introduce an effective treatment. In this paper, we are interested to discussed physcio-chemical properties of Hydroxychloroquine structure and computational work for the specific topological descriptors named as the F-co-index, first Zagreb co-index and first multiplicative Zagreb co-index, second Zagreb co-index and second multiplicative Zagreb co-index.