Electrolyte-gated organic field-effect transistors based on 2,6-dioctyltetrathienoacene as a convenient platform for fabrication of liquid biosensors

• Published in: Russian chemical bulletin 2022-10, Vol.71 (10), p.2116-2122
• Main Authors: Poimanova, E. Yu, Shaposhnik, P. A., Karaman, P. N., Anisimov, D. S., Skorotetcky, M. S., Polinskaya, M. S., Borshchev, O. V., Agina, E. V., Ponomarenko, S. A.
• Format: Article
• Language: English
• Subjects: Benzothiophene; Bioelectricity; Biosensors; Biotin; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Electrolytes; Field effect transistors; Full Articles; Inorganic Chemistry; Organic Chemistry; Semiconductor devices; Semiconductor materials; Stability analysis
• ISSN: 1066-5285; 1573-9171
• DOI: 10.1007/s11172-022-3635-7

Electrolyte-gated organic field-effect transistors (EGOFETs) provide a versatile platform for ultrasensitive, fast, and reliable detection of biological molecules in liquid media using low-cost bioelectronic sensors. The key functional layers of the EGOFETs include the semiconductor and biorecognition layers based on conjugated organic molecules, which must meet high requirements for the operational stability in various electrolytes when detecting analytes. In this work, EGOFETs based on 2,6-dioctyltetrathienoacene as the semiconductor material were fabricated by the doctor blade method compatible with printing technologies. We also report on EGOFETs with the biorecognition layer based on a biotin-containing derivative of [1]benzothieno[3,2- b ]benzothiophene, which was applied by the Langmuir—Schaeffer method. The possibility of stable operation of the fabricated EGOFETs in various electrolytes and their sensor responses to the electrolyte pH value and streptavidin are demonstrated.