Einzelzellmikroskopie im Hochdurchsatz auf Mikrostrukturen

Cellular response to perturbations, if examined at the single cell level, exhibits cell-to-cell differences, distinct dynamic behavior and correlations meaningful for the study of regulatory networks and information processing. Live-cell imaging on single cell arrays (LISCA) facilitates automated ac...

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Bibliographic Details
Published in:Biospektrum 2022-11, Vol.28 (7), p.723-725
Main Authors: Müller, Judith A., Schwake, Gerlinde, Rädler, Joachim O.
Format: Article
Language:ger
Subjects:
Biochemistry
Biomedical and Life Sciences
Human Genetics
Information processing
Life Sciences
Microbiology
Nanoparticles
Pharmacology/Toxicology
Transfection
Wissenschaft Special
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Summary:Cellular response to perturbations, if examined at the single cell level, exhibits cell-to-cell differences, distinct dynamic behavior and correlations meaningful for the study of regulatory networks and information processing. Live-cell imaging on single cell arrays (LISCA) facilitates automated acquisition of individual time courses with sharp temporal resolution. Here we discuss expression dynamics after transient GFP transfection and event-time correlations in nanoparticle induced apotosis.
ISSN:0947-0867
1868-6249
DOI:10.1007/s12268-022-1857-8