Antibacterial and antioxidant activities and phytochemical composition of Stereospermum kunthianum root bark

A new glycoiridoid (1) together with seven (7) known compounds were isolated from the methanol crude extract of the root bark of Stereospermum kunthianum using chromatography methods. Their structures were elucidated using HR-ESI-MS, 1 D- & 2 D-NMR spectroscopies in comparison with previous lite...

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Bibliographic Details
Published in:Natural product research 2022-11, Vol.36 (22), p.5665-5675
Main Authors: Wangso, Honoré, Laya, Alphonse, Leutcha, Peron Bosco, Koubala, Benoît Bargui, Laurent, Sophie, Henoumont, Celine, Talla, Emmanuel
Format: Article
Language:English
Subjects:
Antibacterial activity
antioxidant activity
Antioxidants
Bark
Bignoniaceae
E coli
Infectious diseases
iridoid
Medicinal plants
NMR
Nuclear magnetic resonance
Scavenging
Stereospermum kunthianum
Strains (organisms)
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Summary:A new glycoiridoid (1) together with seven (7) known compounds were isolated from the methanol crude extract of the root bark of Stereospermum kunthianum using chromatography methods. Their structures were elucidated using HR-ESI-MS, 1 D- & 2 D-NMR spectroscopies in comparison with previous literature. The antioxidant activity was investigated by using FRAP, DPPH, ABTS and HRSA methods while the antibacterial activity was assays on Escherichia coli (ATCC25922) and Salmonella typhimurium (ATCC14028) strains. The results showed that the isolated compounds had significantly (p 
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2021.2019730