Pneumomediastinum following Ecstasy (methylenedioxymetamphetamine, MDMA) ingestion in two people at the same ’rave

Ecstasy is a class A controlled drug often consumed by the young population for recreational purposes. Documented complications of its use include hyperpyrexia, disseminated intravascular coagulation (DIC), renal failure and rhabdomyolysis. We report on two patients who developed pneumomediastinum a...

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Bibliographic Details
Published in:Journal of laryngology and otology 2002-01, Vol.116 (1), p.75-76
Main Authors: Rejali, Darius, Glen, Paul, Odom, Nicholas
Format: Article
Language:English
Subjects:
(RF) Otorhinolaryngology
Adult
Amphetamine-Related Disorders
Amphetamine-Related Disorders - complications
Biological and medical sciences
Cocaine
Drug addictions
Ecstasy
Emphysema
Female
Hallucinogens - adverse effects
Humans
Male
Mediastinal Emphysema
Mediastinal Emphysema - chemically induced
Medical sciences
N-Methyl-3,4-methylenedioxyamphetamine - adverse effects
Neck pain
Patients
Pneumology
Respiratory system : syndromes and miscellaneous diseases
Rhabdomyolysis
Toxicology
X-rays
Citations: Items that cite this one
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Description
Summary:Ecstasy is a class A controlled drug often consumed by the young population for recreational purposes. Documented complications of its use include hyperpyrexia, disseminated intravascular coagulation (DIC), renal failure and rhabdomyolysis. We report on two patients who developed pneumomediastinum after Ecstasy abuse. Both patients obtained and consumed the drug at the same establishment and presented to the same hospital within half an hour. The possible pathogenesis of this complication are discussed and the literature reviewed. Pneumomediastinum should be recognized as a possible complication of Ecstasy use. Conservative management is appropriate.
ISSN:0022-2151
1748-5460
DOI:10.1258/0022215021910230