Diagnostic performance of pre-management computed tomography findings as a predictor of conservative treatment success in patients with emphysematous pyelonephritis

Background Emphysematous pyelonephritis (EPN) is one of the most serious urologic emergency which should be diagnosed and treated adequately to prevent impending septic shock and death. Computed tomography (CT) is the gold standard radiologic modality for diagnosis, grading and predicting the outcom...

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Published in:Egyptian journal of radiology and nuclear medicine 2022-12, Vol.53 (1), p.1-7
Main Authors: Badawy, Mohamed Ali, Abdelbaset, Mohamed, Zahran, Mohamed, Ghobrial, Fady Kamal, El-Ghar, Mohamed Abou, Elsorougy, Ali, Abdelhamid, Abdalla
Format: Article
Language:English
Subjects:
Air locules
Antibiotics
Bacterial infections
Care and treatment
Catheters
Chi-square test
Computed tomography
Conservative
Creatinine
CT imaging
Emphysematous pyelonephritis
Fever
Fistula
Hydronephrosis
Laboratories
Management
Medical research
Medicine, Experimental
Morbidity
Mortality
Patients
Prognosis
Pyelonephritis
Septic shock
Success
Tomography
Ultrasonic imaging
Urine
Urogenital system
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Summary:Background Emphysematous pyelonephritis (EPN) is one of the most serious urologic emergency which should be diagnosed and treated adequately to prevent impending septic shock and death. Computed tomography (CT) is the gold standard radiologic modality for diagnosis, grading and predicting the outcome. We aimed in this study to define the initial CT radiological findings correlated with EPN conservative management success. Results This study involved 54 patients (42 women and 12 males) with a mean age of 48 ± 10 years. EPN grades I, II, III, and IV were noticed in 12, 17, 20, and 5 patients, respectively. Ten patients (18.5%) received successful conservative management. On the other hand, renal drainage was needed in 42 patients (77.8%). Delayed nephrectomy was required in two cases (3.7%). In univariate and multivariate analyses, the absence of hydronephrosis and decreased air locules volume were predictors of conservative treatment success (P = 0.003 and 0.01, respectively). Conclusions Conservative therapy should be selected in certain patients of emphysematous pyelonephritis. Decreased air locules volume and the absence of hydronephrosis in pre-admission computed tomography were predictors for conservative therapy success.
ISSN:0378-603X
2090-4762
DOI:10.1186/s43055-022-00941-7