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Reactions of Isonicotinic Acid Hydrazide and Its Trimethylsilyl Derivatives with Isocyanates

Reactions of isonicotinic acid hydrazide and its trimethylsilyl derivatives with hexamethyldisilazane, organic, and organosilicon isocyanates were studied. The possibility of synthesizing previously unknown isoniazid derivatives by preliminary introduction of a trimethylsilyl substituent to the nitr...

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Bibliographic Details
Published in:Russian journal of general chemistry 2022-11, Vol.92 (11), p.2223-2227
Main Authors: Belova, L. O., Golub, N. A., Pletneva, M. V., Kirilina, N. I., Kirilin, A. D.
Format: Article
Language:English
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Summary:Reactions of isonicotinic acid hydrazide and its trimethylsilyl derivatives with hexamethyldisilazane, organic, and organosilicon isocyanates were studied. The possibility of synthesizing previously unknown isoniazid derivatives by preliminary introduction of a trimethylsilyl substituent to the nitrogen atom was established.
ISSN:1070-3632
1608-3350
DOI:10.1134/S1070363222110032