The Putamen Increases Influence Over a Brain Network During Insulin Pulsation: The Brain-Body Connection Study

Background: Insulin affects brain activity, likely as part of a pancreatic-brain feedback loop. Previous research on insulin and the brain has relied on external intra-nasal insulin, rather than endogenously secreted insulin. These methods preclude evaluating the dynamic changes in brain connectivit...

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Bibliographic Details
Published in:Obesity (Silver Spring, Md.) Md.), 2022-11, Vol.30, p.204-205
Main Authors: Shearrer, Grace, Akhmadjonova, Muzayyana, Hall, Lucy, Rajic, Benjamin, Tregellas, Jason, Cree-Green, Melanie, Nadeau, Kristen, Shapiro, Allison
Format: Article
Language:English
Subjects:
Brain research
Insulin
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Summary:Background: Insulin affects brain activity, likely as part of a pancreatic-brain feedback loop. Previous research on insulin and the brain has relied on external intra-nasal insulin, rather than endogenously secreted insulin. These methods preclude evaluating the dynamic changes in brain connectivity in response to physiologic insulin pulses. Methods: The present analysis evaluated the changes in temporal brain connectivity corresponding 4.6y, HbA1c
ISSN:1930-7381
1930-739X