Quinoxalin‐2(1H)‐ones: Chemical Synthesis, Fluorescence Properties and Applications

Photophysical properties of quinoxalin‐2(1H)‐ones have long been neglected, in particular compared with those of coumarins, their oxygenated counterparts, despite their complementarity in terms of absorbance and fluorescence windows. This review provides first an overview of the synthesis of quinoxa...

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Published in:European journal of organic chemistry 2022-12, Vol.2022 (48), p.n/a
Main Authors: Renault, Kévin, Renard, Pierre‐Yves, Sabot, Cyrille
Format: Article
Language:English
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biological applications
Chemical synthesis
Fluorescence
imaging applications
quinoxalin-2(1H)-one
synthesis
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description Photophysical properties of quinoxalin‐2(1H)‐ones have long been neglected, in particular compared with those of coumarins, their oxygenated counterparts, despite their complementarity in terms of absorbance and fluorescence windows. This review provides first an overview of the synthesis of quinoxalin‐2(1H)‐ones, focusing on the most recent contributions. Fluorescence properties of quinoxalin‐2(1H)‐ones and of their π‐extended derivatives are tackled through the description of a series of examples and applications, including chemosensing and biosensing. This review summarized the synthesis and fluorescence properties of quinoxalin‐2(1H)‐ones and their π‐extended derivatives. Subsequent applications, including chemosensing and biosensing are also reported.
doi_str_mv 10.1002/ejoc.202201314
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subjects biological applications
Chemical synthesis
Fluorescence
imaging applications
quinoxalin-2(1H)-one
synthesis
title Quinoxalin‐2(1H)‐ones: Chemical Synthesis, Fluorescence Properties and Applications
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