Cytokine Storm, Immunomodulators and Mucormycosis in COVID-19: Bench To Bed Side

The world is undergoing its biggest health crisis named coronavirus disease, which is associated with increased proinflammatory cytokine storm, which ultimately leads to various medical complications including acute respiratory distress syndrome. The treatment protocol was always controversial due t...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2022-11, Vol.15 (11), p.4871-4875
Main Authors: T Kondody, Rony, Rama Varma, Sudhir, Patil, Aishwarya, Nambiar, Manjusha, S Nair, Arathi, Mathew, Rhea, PT, Abhishek
Format: Article
Language:English
Subjects:
Antibodies
Chemokines
Coronaviruses
COVID-19
Cytokine storm
Diabetes
Disease transmission
Fungal infections
Immune system
Immunomodulators
Immunotherapy
Infections
Inflammation
Liver
Medical research
Mortality
Pneumonia
Sepsis
Severe acute respiratory syndrome coronavirus 2
Steroids
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Summary:The world is undergoing its biggest health crisis named coronavirus disease, which is associated with increased proinflammatory cytokine storm, which ultimately leads to various medical complications including acute respiratory distress syndrome. The treatment protocol was always controversial due to the excessive use of corticosteroids in aggressive pneumonia and associated hyperinflammatory conditions.The excessive use, misuse, and rampant use of steroids may lead to various coinfection like mucormycosis which is referred to as black fungus that manifests within the skin and also affects the lungs and brain which may be more fatal. It is necessary to have early diagnosis and management to tackle the severity of post covid coinfection.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2022.00818