Valvular heart disease in pregnancy

Key content Pregnancy‐induced changes in haemodynamic physiology can place considerable strain on cardiac function in some women with valvular disease. Regurgitant valve lesions are usually better tolerated in pregnancy than stenotic lesions, although the risk of obstetric complications is increased...

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Bibliographic Details
Published in:The obstetrician & gynaecologist 2023-01, Vol.25 (1), p.19-27
Main Authors: Timmons, Paul, Partridge, Gemma, McKelvey, Alastair, Lyall, Hamish, Morosan, Monica, Freeman, Leisa
Format: Article
Language:English
Subjects:
analgesia
Anticoagulants
Cardiovascular disease
haematology
Hemodynamics
maternal physiology
medical disorders in pregnancy
obstetric
Pathophysiology
Pregnancy
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Summary:Key content Pregnancy‐induced changes in haemodynamic physiology can place considerable strain on cardiac function in some women with valvular disease. Regurgitant valve lesions are usually better tolerated in pregnancy than stenotic lesions, although the risk of obstetric complications is increased in both. Pre‐conception counselling is essential for all women with valvular disease. Optimising anticoagulation is a particular challenge in women with mechanical valves. Learning objectives To understand the World Health Organization (WHO) classification of maternal cardiac disease and how this affects counselling regarding decisions around pregnancy for women with valve pathology. To understand how valve disease affects pregnancy and vice versa. To gain insight into the anaesthetic and haematological considerations for managing women with valvular disease. Ethical issues What is the optimum anticoagulation regimen for women with mechanical heart valves in pregnancy that balances both maternal and fetal risks?
ISSN:1467-2561
1744-4667
DOI:10.1111/tog.12857