The combination of N-Acetyl-L-Cysteine, Pelargonium sidoides and Justicia adhatoda (NAXX) exerts bacteriostatic activity against S. aureus and E. coli

Many herbal agents and medicinal plants have provided clinical interest due to their therapeutic properties, availability and lower side effects. The aim of this study was to understand the anti-bacterial activity of the combination of Pelargonium sidoides (PEL), Justicia adhatoda (ADH) and N-Acetyl...

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Bibliographic Details
Published in:Natural product research 2021-12, Vol.35 (23), p.5360-5363
Main Authors: Terlizzi, Michela, Colarusso, Chiara, Di Maio, Umberto, Pinto, Aldo, Sorrentino, Rosalinda
Format: Article
Language:English
Subjects:
Acetylcysteine
anti-microbial activity
anti-oxidant
Antibacterial activity
Bacteriostats
Cysteine
E coli
Herbal medicine
Justicia adhatoda
Medicinal plants
Microorganisms
N-Acetyl-L-Cysteine
Oxidants
Oxidative stress
Oxidizing agents
Pelargonium sidoides
Plants
Side effects
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Summary:Many herbal agents and medicinal plants have provided clinical interest due to their therapeutic properties, availability and lower side effects. The aim of this study was to understand the anti-bacterial activity of the combination of Pelargonium sidoides (PEL), Justicia adhatoda (ADH) and N-Acetyl-L-Cysteine (NAC) (NAXX). We found that NAXX had strong and long-term bacteriostatic activity, which was related to its anti-oxidant activity. Our data demonstrate that NAXX is an innovative medicinal plant-derived strategy to manage of oxidative stress- and microbial-based diseases.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2020.1761359