Congenital systemic chondrodysplasia in a white lion (Panthera leo)

The death of a 6‐month‐old, male, white lion with micrognathia and short, thick limbs in a zoo prompted postmortem whole‐body computed tomography and head magnetic resonance imaging to be performed. Computed tomography revealed malformation of all bones. The metaphyses of the long bones were enlarge...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary record case reports 2023-03, Vol.11 (1), p.n/a
Main Authors: Kutara, Kenji, Kadekaru, Sho, Sugisawa, Reiko, Saito, Fumiyo, Une, Yumi
Format: Article
Language:English
Subjects:
Case reports
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The death of a 6‐month‐old, male, white lion with micrognathia and short, thick limbs in a zoo prompted postmortem whole‐body computed tomography and head magnetic resonance imaging to be performed. Computed tomography revealed malformation of all bones. The metaphyses of the long bones were enlarged and showed fraying and cupping. Moreover, magnetic resonance imaging revealed abnormal bone tissue with reduced bone density, severe bilateral compression of the spinal cord from the stomach up to the level of the atlas and herniation of the cerebellar vermis. Histopathological examination revealed that the metaphyses of all long bones were enlarged and replaced with cartilage; however, the structure of the joints was maintained. This report presents the first case of congenital systemic chondrodysplasia identified by postmortem examination and imaging in a lion.
ISSN:2052-6121
2052-6121
DOI:10.1002/vrc2.534