Ischemic heart disease in correlation with some immunological parameters

Sixty five Ischemic heart disease (IHD) patients and 25 healthy control were included in this work. 90.7% hypertensive patients and 66% of patients were with diabetes. Serum samples were tested for interleukin-17A (IL-17A), interleukin-17A Receptor (IL-17AR) and interleukin-12/23p40 (IL-12/23p40) us...

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Bibliographic Details
Main Authors: Abd, Wisal Salman, Abd, Najah Salman
Format: Conference Proceeding
Language:English
Subjects:
Heart diseases
Immunology
Interleukins
Pathogenesis
Online Access:Get full text
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Summary:Sixty five Ischemic heart disease (IHD) patients and 25 healthy control were included in this work. 90.7% hypertensive patients and 66% of patients were with diabetes. Serum samples were tested for interleukin-17A (IL-17A), interleukin-17A Receptor (IL-17AR) and interleukin-12/23p40 (IL-12/23p40) using Sandwich ELISA technique, Mean serum levels as compared to healthy of 17A, IL-17AR and IL-12/23p40 were 57.5±2.6 pg/ml, 37.3±5.1 pg/ml and 301±43.3 pg/ml compared to healthy control groups 11.7±1.7pg/ml, 7.3±1.0pg/ml and 10.4±3.6pg/ml respectively. It could be concluded that the prevalence of IHD in a diabetic patients is higher than control, IL-17A, IL-17AR and IL-12/23p40 have a role in diagnosis, and IL-12 and IL-23 play a crucial role in pathogenesis of IHD.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0116787