36 Evaluating the effect of lower limb botulinum toxin a injections on goal-directed outcomes in ambulant children and young people with cerebral palsy

BackgroundBotulinum toxin-A (BoNT-A) is used in management of hypertonia in children and young people with cerebral palsy (CYPwCP). Evidence is limited regarding its effect on goal-directed outcome measures. Meaningful child-and-family-centred goal identification is an essential element of rehabilit...

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Published in:Archives of disease in childhood 2023-02, Vol.108 (Suppl 1), p.A13-A14
Main Authors: Katchburian, Lesley, Hodgson, Xanthe, Crowe, Belinda, Carr, Lucinda, Main, Eleanor, Oulton, Kate
Format: Article
Language:English
Subjects:
Botulinum toxin
Cerebral palsy
Children
Classification
Environmental factors
Environmental Influences
Injection
Longitudinal studies
Outcome Measures
Paralysis
Pediatrics
Posters presentations
Rehabilitation
Structure-function relationships
Toxins
Young Adults
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Summary:BackgroundBotulinum toxin-A (BoNT-A) is used in management of hypertonia in children and young people with cerebral palsy (CYPwCP). Evidence is limited regarding its effect on goal-directed outcome measures. Meaningful child-and-family-centred goal identification is an essential element of rehabilitation, ensuring interventions are targeted towards children’s individual priorities. This prospective single site study assessed goal attainment in CYPwCP undergoing BoNT-A injections using the Canadian Occupational Performance Measure (COPM).MethodsData were collected from 64 ambulant CYPwCP (Gross Motor Function Classification System levels I-III) aged 4 to 16 years undergoing lower limb BoNT-A injections within the movement disorder service at GOSH. Changes in COPM scores were analysed at 6-weeks, 6-months and 12-months post-intervention using Friedman tests. Participants’ goals were classified according to the International Classification of Functioning, Disability and Health domains of Body Structure and Function, Activity and Participation and Environmental Factors.ResultsCOPM performance scores improved significantly from baseline to 6-weeks (median difference 3.17; p-value
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2023-gosh.36